Abstract
BY administration of œstrogen the corpora lutea of the rabbit can be maintained after hypophy-sectomy, and prolonged beyond the normal term of pseudopregnancy; and these corpora can be presumed to be functional1,2. Recently3, it has been shown that the maintenance is a direct effect of œstrogen on the luteal tissue. Implantation of, for example, stilbœstrol dipalmitate or dibutyrate directly into a corpus will cause maintenance of adjacent luteal cells when in other corpora they have degenerated following hypophysectomy, parturition, or the end of the normal period of pseudopregnancy. However (though it is probable enough), it is not certain that luteal function, as well as structure, is directly maintained by œstrogen.
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References
Westman, A., and Jacobsohn, D., Acta Obst. et Gynec. Scandinav., 17, 1 (1937).
Robson, J. M., J. Physiol., 90, 435 (1937).
Hammond, J., jun., and Robson, J. M., Endocrin., 49, 384 (1951).
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HAMMOND, J. Maintenance of Grafted Rabbit Luteal Tissue. Nature 169, 330–331 (1952). https://doi.org/10.1038/169330b0
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DOI: https://doi.org/10.1038/169330b0
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