Abstract
Gillman, Gilbert, Gillman and Spence in a recent paper1 reported a series of malformations obtained in newborn rats as a result of injection of the dye trypan blue into female rats during varying stages of pregnancy. One of the interesting features of these malformations in rats is their remarkable resemblance to abnormalities known to occur in mice as effects of mutations2,3.
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Gillman, J., Gilbert, Ch., Gillman, Th., and Spence, I., S. Afr. J. Med. Sci., 13, 47 (1948).
Dunn, L. C., Harvey Lectures, 35, 135 (1940).
Gluecksohn-Schoenheimer, S., Genetics, 23, 573 (1938).
Gluecksohn-Waelseh, S., “Advances in Genetics”, 4, 2 (1951).
Bonnevie, K., Skrif. Norske Vid. Akad., 2, 1 (1936).
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HAMBURGH, M. Malformations in Mouse Embryos induced by Trypan Blue. Nature 169, 27 (1952). https://doi.org/10.1038/169027a0
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DOI: https://doi.org/10.1038/169027a0
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