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Bacterial Enzyme Preparations oxidizing Inositol and their Inhibition by Colchicine

Abstract

PREVIOUS studies in this laboratory have brought to light a number of regularities governing the oxidation of isomers of the inositol group by resting Acetobacter suboxydans1,2. If the hexahydroxy by cyclo-hexanes are formulated as existing in the chair configuration, the minimum steric requirements for the oxidation of the various isomers by the resting cells are described in the statement that only those hydroxyl groups are oxidized that are situated in a polar plane.

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References

  1. Chargaff, E., and Magasanik, B., J. Biol. Chem., 165, 379 (1946).

    CAS  PubMed  Google Scholar 

  2. Magasanik, B., and Chargaff, E., J. Biol. Chem., 174, 173; 175, 929, 939 (1948).

    CAS  PubMed  Google Scholar 

  3. Franzl, R. E., and Chargaff, E., Fed. Proc., 9, 173 (1950).

    Google Scholar 

  4. Kluyver, A. J., and Boezaardt, A. G. J., Rec. trav. chim. Pays-Bas, 58, 956 (1939).

    Article  CAS  Google Scholar 

  5. Posternak, T., Helv. Chim. Acta, 29, 1991 (1946).

    Article  Google Scholar 

  6. Cook, J. W., and Loudon, J. D., Quart. Rev., Chem. Soc., London, 5, 99 (1951).

    Article  CAS  Google Scholar 

  7. Doering, W. von E., and Knox, L. H., J. Amer. Chem. Soc., 72, 2305 (1950); 73, 828 (1951).

    Article  CAS  Google Scholar 

  8. Cook, J. W., Gibb, A. R., Raphael, R. A., and Somerville, A. R., Chem. and Indust., 427 (1950).

  9. Haworth, R. D., and Hobson, J. D., Chem. and Indust., 441 (1950).

  10. Chargaff, E., Stewart, R. N., and Magasanik, B., Science, 108, 556 (1948).

    Article  ADS  CAS  Google Scholar 

  11. Murray, M. R., de Lam, H. H., and Chargaff, E., Exp. Cell Res., 2, 165 (1951).

    Article  CAS  Google Scholar 

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FRANZL, R., CHARGAFF, E. Bacterial Enzyme Preparations oxidizing Inositol and their Inhibition by Colchicine. Nature 168, 955–957 (1951). https://doi.org/10.1038/168955b0

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