Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Effect of Ascorbic Acid on Skin Permeability in Adrenalectomized Rats

Nature volume 168, pages 119–120 (1951)Cite this article

Abstract

IN recent years, facts have accumulated about the composition of the ground substance of the connective tissue proper. In loose connective tissue, this amorphous matrix consists of a highly viscous gel built up by acid mucopolysaccharides like hyaluronic acid and mucoitin sulphuric acid. The ground substance obviously is a very labile structure in respect of its physical and chemical composition. Among the agents that may have an influence on the composition of the interfibrillar gel, the adrenocortical hormones and ascorbic acid have attracted much attention.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Opsahl, Jeanette C., Yale J. Biol. and Med., 21, 255 (1949).

    CAS  Google Scholar 

  2. Opsahl, Jeanette C., Yale J. Biol. and Med., 21, 487 (1949).

    CAS  Google Scholar 

  3. Opsahl, Jeanette C., White, A., and Duran-Reynals, F., Ann. N.Y. Acad. Sci., 52, Art 7, 1061 (1950).

    Article  ADS  CAS  Google Scholar 

  4. Menkin, V., Wolbach, S. B., and Menkin, M. F., Amer. J. Path., 10, 569 (1934).

    CAS  PubMed  Google Scholar 

  5. Penney, J. R., and Balfour, B. M., J. Path. Bact., 61, 171 (1949).

    Article  CAS  Google Scholar 

  6. Wassén, E., and Levin, E., Lancet, ii, 1134 (1949).

  7. Shuman, C. R., and Finestone, A. J., Proc. Soc. Exp. Biol. Med., 73, 248 (1950).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Histological Department, University of Uppsala,

    BENGT H. PERSSON

Authors
  1. BENGT H. PERSSON
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

PERSSON, B. Effect of Ascorbic Acid on Skin Permeability in Adrenalectomized Rats. Nature 168, 119–120 (1951). https://doi.org/10.1038/168119a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/168119a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing