Abstract
Nath and Brahmachari1 have shown the hyperglycæmic effect of injections of sodium acetoacetate in rabbits. Lazarow2 has attempted to correlate the diabetogenic action of some chemical compounds with their ability to lower the reduced glutathione content of the blood. With the view of finding whether acetoacetic acid influences the reduced glutathione content of blood, some experiments were conducted on rabbits. The number of animals used was ten.
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References
Nath, M. C., and Brahmachari, H. D., Nature, 154, 487 (1944).
Lazarow, A., Physiol. Rev., 29, 48 (1949).
Goss, H., and Gregory, P. W., Proc. Soc. Exp. Biol. and Med., 32, 681 (1935). Gregory, P. W., and Goss, H., Growth, 3, 159 (1939).
Conn et al., J. Lab. and Clin. Med., 33, 651 (1948).
Leech, R. S., and Bailey, C. C., J. Biol. Chem., 157, 525 (1945).
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NATH, M., HATWALNE, V. Effect of Acetoacetic Acid on Reduced Glutathione Content of Blood in Rabbits. Nature 166, 692–693 (1950). https://doi.org/10.1038/166692b0
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DOI: https://doi.org/10.1038/166692b0
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