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Inhibition of the Growth of Leuconostoc mesenteroides by the Toxic Factor from ‘Agenized’ Zein: Reversal by L-Glutamine

Abstract

THE crystalline toxic factor originally isolated1 from zein treated with nitrogen trichloride causes epileptiform fits in certain animals and inhibits the growth of Leuconostoc mesenteroides P-602. The subsequent synthesis of the factor from methionine, reported3 from this laboratory, indicates that it probably has the structure CH3.SO(NH).CH2.CH2.CH(NH2)COOH which, formally, has some resemblance to that of glutamine.

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HEATHCOTE, J., PACE, J. Inhibition of the Growth of Leuconostoc mesenteroides by the Toxic Factor from ‘Agenized’ Zein: Reversal by L-Glutamine. Nature 166, 353–354 (1950). https://doi.org/10.1038/166353a0

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