Abstract
THE isolation of more abundant natural compounds mostly uses very simple means—extraction, distiltion, crystallization—and combinations and refinements of these methods. The problem of isolatiing, less abundant natural substances is associated with two outstanding difficulties. The scale of the extraction process is much greater, and the desired material is often accompanied by a variety of very similar materials. Without doubt chromatography has done more than any other experimental advance to overcome these difficulties.
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COOK, A. Chromatographic Separation of Natural Compounds. Nature 164, 300–302 (1949). https://doi.org/10.1038/164300a0
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DOI: https://doi.org/10.1038/164300a0
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