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Effect of Nitrogen Mustard on an Inherited Character in the Rat

Abstract

MUTATIONS induced by chemicals have been observed in a large variety of lower animals and plants. The only experiments on mammals, however, are those reported recently by Auerbach and Falconer1. These authors observed, after treatment of male mice with nitrogen mustard and crossing and back-crossing the offspring of the treated animals, one mutant in one of sixteen animals.

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References

  1. Auerbach, C., and Falconer, D. S., Nature, 163, 678 (1949).

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  2. Ellinger, P., Abstracts of Communications of the 1st International Congress of Biochemistry, 50 (1949).

  3. Ford, E. B., "Genetics for Medical Students", 57 (Methuen and Co., Ltd., London. 3rd edit., 1948).

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ELLINGER, P. Effect of Nitrogen Mustard on an Inherited Character in the Rat. Nature 164, 1095–1096 (1949). https://doi.org/10.1038/1641095b0

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