Abstract
DURING work on ribonucleic acid turnover with nitrogen-15 in this Department, we found it necessary to isolate the different nitrogen-containing substances from small amounts of ribonucleic acid. It was thought that partition chromatography on starch as introduced by Elsden and Synge1 might give a possible solution to our problem. Vischer and Chargaff2 have applied partition chromatography on paper to the purine-bases; Edman, Hammarsten, Löw and Reichard3 have worked out a method for separating guanine and adenine on a starch column. Tinker and Brown4 have recently applied Craig‘s counter-current distribution technique to purines and pyrimidines and related compounds.
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REICHARD, P. Partition Chromatography on Starch of Ribonucleosides. Nature 162, 662 (1948). https://doi.org/10.1038/162662a0
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DOI: https://doi.org/10.1038/162662a0
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