Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Article
  • Published:

Structure of an Animal Virus

Abstract

BECAUSE of their crystallinity, a great deal is known about the ultimate chemical structure of the plant viruses, whereas little or no corresponding information is available for the animal viruses. Efforts to obtain X-ray diffraction patterns have not been successful, and attention has been turned in recent years towards the electron microscope as the tool most likely to solve the problem. For obvious reasons attention in the first instance has been directed to the larger animal viruses, but with the exceptions of nuclei-like bodies in the Rickettsise1 and less definite internal bodies in the pox group2,3, this technique has also proved disappointing. It is clear on the practical side that the size and density of the infective particles is such that 100-kV. electrons can only just penetrate them, and any internal differences in electron density which may exist must be of a low order—probably less than 20 per cent.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  • Plotz, H., Smadel, J. E., Anderson, T. F., and Chambers, L. A., J. Exp. Med., 77, 355 (1943).

    Article  CAS  Google Scholar 

  • Green, R. H., Anderson, T. F., and Smadel, J. E., J. Exp. Med., 75, 651 (1942).

    Article  CAS  Google Scholar 

  • Ruska, H., and Kausche, E. A., Zbl. Bakt., 150, 311 (1943).

    CAS  Google Scholar 

  • Sharp, D. G., Taylor, A. R., Hook, A. E., and Beard, J. W., Proc. Soc. Exp. Biol. Med., 61, 259 (1946).

    Article  CAS  Google Scholar 

  • Boswell, F. W., Brit. J. Exp. Path., 88, 253 (1947).

    Google Scholar 

  • Hopwood, F. L., Salaman, M. H., and McFarlane, A. S., Nature, 144, 377 (1939).

    Article  ADS  CAS  Google Scholar 

  • Hoagland, C. L., Lavin, G. S., Smadel, J. E., and Rivers, T. M., J. Exp. Med., 72, 139 (1940).

    Article  CAS  Google Scholar 

  • Wolpers, C., Naturwiss., 416, 28 (1941).

    Google Scholar 

  • Ponder, E., "The Mammalian Red Cell and the Properties of Hæmolytic Systems", Protoplasma Monographien, 6 (Berlin, Borntraeger, 1942).

    Google Scholar 

  • Ponder, E., J. Gen. Physiol., 29, 89 (1945).

    Article  CAS  Google Scholar 

  • Teitel-Barnard, A., Arch. Roum. Path., 5, 389 (1932).

    Google Scholar 

  • Schmidt, W. G., Kolloidzschr., 85, 137 (1938).

    CAS  Google Scholar 

  • Moore, A. R., and Miller, W. A., Proc. Soc. Exp. Biol., 36, 835 (1937).

    Article  Google Scholar 

  • Anderson, T. F., Cold Spring Harbor Symposia, 11, 1 (1946).

  • Dubos, R. J., "The Bacterial Cell" (Harvard Univ. Press, 1945).

    Google Scholar 

  • Wyckoff, R. W. G., Proc. Soc. Exp. Biol. Med., 66, 42 (1947).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

DAWSON, I., McFARLANE, A. Structure of an Animal Virus. Nature 161, 464–466 (1948). https://doi.org/10.1038/161464a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/161464a0

This article is cited by

Comments

By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing