Abstract
Bacterium coli, inoculated in broth, metabolizes the culture medium producing alkalinization, bringing the pH to 8.5 and more. These are the standard conditions we used to obtain penicillinase1.
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References
Gorini, L., and Torriani, A., Boll. Soc. Ital. Biol. Sper., 22, 1269 (1946).
Gale, âœAdvances in Enzymol.â, 6, 1.
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GORINI, L., TORRIANI, A. Biochemistry of Escherichia coll and the Production of Penicillinase. Nature 160, 332–333 (1947). https://doi.org/10.1038/160332a0
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DOI: https://doi.org/10.1038/160332a0
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