Abstract
INVESTIGATIONS of the prenatal mortality in wild rabbits1,2,3 led us to examine embryologically many 8-, 9- and 10-day embryos. It was found that in a substantial proportion of these the yolk sac content could be seen macroscopically to be gelatinous and to contain an irregular network of fine fibrils. Microscopic examination revealed the presence of a fine reticulum in the yolk sac. This reticulum resembled histologically sections of a fibrin clot prepared from blood plasma that had been fixed and stained by the same technique. For this and other reasons it was suspected that the reticulum in the yolk sac was, in fact, fibrin.
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Brambell, F. W. R., Proc. Roy. Soc., B, 130, 462 (1942).
Brambell, F. W. R., Proc. Zool. Soc. Lond., 114, 1 1944).
Brambell, F. W. R., and Mills, I. H., Nature, 153, 558 (1944).
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BRAMBELL, F., MILLS, I. Presence of Fibrinogen in the Yolk Sac Content of Rabbits. Nature 158, 24 (1946). https://doi.org/10.1038/158024a0
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DOI: https://doi.org/10.1038/158024a0
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