Abstract
IN cancer therapy it is of great interest to distinguish between tumours according to their degree of mitotic activity. This requires a determination of the proportion of dividing to resting cells. It may even be useful to follow the character of mitosis after X-ray treatment. Human cells are difficult to handle for this purpose. The usual techniques are tedious and unsatisfactory. Indeed, misleading conclusions have often been reached owing to the inadequacy of the preparations used. In contrast with the older methods, I find that La Cour's acetic-lacmoid (resorcin-blue) treatment1 is rapid and, as may be seen from the photographs, capable of showing both the character as well as the stage of division.
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References
Darlington, C. D., and La Cour, L. F., "The Handling of Chromosomes" (Allen and Unwin, London, 1942).
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KOLLER, P. A New Technique for Mitosis in Tumours. Nature 149, 193 (1942). https://doi.org/10.1038/149193a0
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DOI: https://doi.org/10.1038/149193a0
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