Abstract
RECENTLY, Slottaand Fraenkel-Conrat1,2 reported that they have succeeded in separating the whole of the neurotoxin and hæmolysin of Crotalus-t-terrificus venom in a crystalline form, and that repeated recrystallization of this substance did not change its physiological properties or its chemical composition. This crystalline substance containing both neurotoxic and hæmolytic activities was considered by them to be a pure substance. In the course of our investigation on the separation of the various active principles of Crotalus-t-terrificus venom we have found that the hæmolysin can be partially separated from the neurotoxin by adopting the following procedure:
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References
Slotta, K. H., and Fraenkel-Conrat, H., NATURE, 142, 213 (1938).
Slotta, K. H., and Eraenkel-Conrat, H., Ber. deutsch. chem. Ges., 11, 1623 (1938).
Ghosh, B. N., and De, S. S., Science and Culture, 585 (May 1937).
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GHOSH, B., DE, S. Proteins of Rattlesnake Venom. Nature 143, 380–381 (1939). https://doi.org/10.1038/143380b0
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DOI: https://doi.org/10.1038/143380b0
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