Abstract
BOTH 4-methylcyclohexane-l-carboxy-l-succinic acid and 3-methylcyclohexane-l-carboxy-l-succinic acid, synthesized by condensation of ethyl bromoacetate with the sodio derivatives of the dicyano esters prepared by Higson and Thorpe's method1, have been isolated in two forms ; there being no indication of isomerism connected with multiplanar forms2. This method provides a satisfactory synthesis of the tricarballylic acids derived from cyclic ketones, and the low yield of -dimethyltricarballylic acid obtained from acetone3 can be raised to nearly 30 per cent by suitable modification of the method. The conversion of the tricarballylic derivatives into the corresponding aconitic acids is being investigated.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Higson and Thorpe, J. Chem. Soc., 89, 1455 (1906).
Desai, Hunter, Ghulam Khan and Saharia, J. Chem. Soc., 416 (1936); Waheed Bukhsh, Desai, Hunter and Mehdi Hussain, J. Chem. Soc., 1159 (1936); Desai, Farooq and Hunter, J. Chem. Soc., 1162 (1936).
Clemo and Welch, J. Chem. Soc., 2621 (1928).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
DESAI, R., HUNTER, R. & SAHARIA, G. Isomerism of Derivatives of Cyclohexane. Nature 139, 718–719 (1937). https://doi.org/10.1038/139718b0
Issue Date:
DOI: https://doi.org/10.1038/139718b0
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.
