Dr C Jelleff Carr, a founding father of the International Society of the Regulatory Toxicology and Pharmacology (ISRTP), secretary of the Society for 20 years and managing editor of the Journal Regulatory Toxicology and Pharmacology since the inception, died on February 15, 2005, a few days short of his 95th birthday.

Jeff was a man of few words, a trait that belied the many subjects he could address with profound competence. Born in Towson, Maryland, he rose with full scholarships to earn his PhD in pharmacology in 1937. His career was stellar. The functions and safety of now common sugar substitutes were established through his pioneering efforts. His studies laid the foundations of modern anesthetics that are the mainstay of surgery practice worldwide. Some of the most effective cardiovascular medicines were first conceived through his research.

As the responsible scientist attached to the Army General Staff, he supervised medical and alimental provisions for the Vietnam Campaign. Later he founded and directed the Life Sciences Research Office, the Federation of American Societies of Experimental Biology, where he was instrumental in steering major regulatory policies in food safety and medicine, obtaining international recognition and following.

For 20 years a professor of pharmacology at the Medical School, University of Maryland, with JC Krantz he coauthored textbook Pharmacologic Principles of Medical Practice that became the standard in the education of generations physicians in North and South America, India, Australia, South Africa, and the Philippines. His scientific influence touched uncounted millions of people in four continents.

A multitude of friends marveled at his optimistic, serene, and self-effacing demeanor, and came to deeply admire this gentle and kind man who gave and was giving so much, asking nothing in return. Jeff Carr will be missed, and will be remembered.

C Jelleff Carr a member of the American College of Neuropsychopharmacology (ACNP); he was accepted in 1961. He was a Life Fellow Emeritus.