Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Original Article
  • Published:

The use of ambulatory blood pressure monitoring in managing hypertension according to different treatment guidelines

Abstract

Objective: To investigate the use of ambulatory blood pressure monitoring (ABPM) in identifying and managing a group of patients referred to a tertiary centre for the assessment of their blood pressure and to illustrate the importance of introducing standardised ABPM treatment guidelines.

Patients and methods: We examined 2000 sequential ABP recordings, 1557 were first time referrals from General Practitioners, Consultants and other hospitals. All patients were referred with suspected hypertension, resistant hypertension, white coat hypertension and for investigations of secondary hypertension. Fully trained nurse specialists fitted the monitors in the hypertension clinic and recordings were performed for 24 h. The data was then analysed and stratified according to treatment guidelines and categorised according to different definitions.

Results: The group of first time referrals (n = 1557) showed an even sex distribution of 789 men and 768 women, mean age 53 ± 13.8 (12–88 years). Of this group 542 patients (35%) exhibited a white coat effect (WCE), 526 (34%) had a daytime ABP ≤139/89 mm Hg. Of these 81 (15%) had a high clinic blood pressure (ie, white coat hypertension (WCH)) according to our definition. Thirty-five of these patients were not on treatment but may have had it initiated on the basis of their clinic pressures. According to the British Hypertension Society (BHS) guidelines on clinic readings 772 (45%) of our patients would be classified as hypertensive or inadequately treated, 509 (33%) borderline and 326 (21%) as normal. Using daytime ABP levels according to O’Brien: 1031 (67%) would be defined as abnormal, 192 (12%) as borderline and 334 (21%) as normal.

Conclusion: These results illustrates how patient management may differ markedly when treating in accordance either with the BHS guidelines for clinic readings or the suggested levels for ABP. More patients had abnormal blood pressure levels according to ABPM, even though it is superior in detecting WCE and WCH. Clear guidelines for ABPM treatment levels need to be established.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Purcell H, Gibbs S, Coats A, Fox K Ambulatory blood pressure monitoring and circadian variations of cardiovascular disease; clinical and research applications Int J Cardiol 1992 36 135–149

    Article  CAS  PubMed  Google Scholar 

  2. Mancia G et alBlood pressure reduction and end-organ damage in hypertension J Hypertens 1994 12 (Suppl 8) S35–S40

    Google Scholar 

  3. Verdecchia P et alWhite-coat hypertension: not guilty when correctly defined Blood Press Monit 1998 3 147–152

    CAS  PubMed  Google Scholar 

  4. Coats A Reproducibility or variability of causal and ambulatory blood pressure data: implications for clinical trials J Hypertens 1990 8 (Suppl 6) S17–S20

    Google Scholar 

  5. Clark S et alAmbulatory blood pressure monitoring: validation of the accuracy and reliability of the TM 2420 according to the AAMI recommendations Hum Hypertens 1991 5 77–82

    CAS  Google Scholar 

  6. Ramsay L et alGuidelines for the management of hypertension: report of the third working party of the British Hypertension Society J Hum Hypertens 1999 13 569–592

    Article  CAS  PubMed  Google Scholar 

  7. O'Brien E et alWhat are the normal levels for ambulatory blood pressure measurement? Blood Press Monit 1998 3 131–132

    CAS  PubMed  Google Scholar 

  8. Management Committee on behalf of High Blood Pressure Research Council of Australia Australian comparative outcome trial of angiotensin-converting enzyme inhibitor and diuretic-based treatment of hypertension in the elderly (ANBP2): objectives and protocol Clin Exp Pharmacol Physiol 1997 24 188–192

    Article  Google Scholar 

  9. Chalmers J et alWHO-ISH Hypertension Guidelines Committee. 1999 World Health Organisation–International Society of Hypertension Guidelines for the Management of Hypertension J Hypertens 1999 17 151–185

    Google Scholar 

  10. O’Brien E, Staessen J Commentary What is ‘hypertension’? Lancet 1999 353 1541–1542

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to C Addison.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Addison, C., Varney, S. & Coats, A. The use of ambulatory blood pressure monitoring in managing hypertension according to different treatment guidelines. J Hum Hypertens 15, 535–538 (2001). https://doi.org/10.1038/sj.jhh.1001210

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/sj.jhh.1001210

Keywords

This article is cited by

Search

Quick links