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  • New Themes in Hypertension: Proceedings of The Eighth Symposium of The London Hypertension Society
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New Themes in Hypertension: Proceedings of the Eighth Symposium of the London Hypertension Society

Evidence of platelet activation in hypertension

Journal of Human Hypertension volume 11, pages 607–609 (1997)Cite this article

Abstract

To test the hypothesis that platelet activation is present in hypertension, we measured plasma markers beta thromboglobulin and soluble P-selectin in hypertensive patients and normotensive controls. Both markers were raised in the patients (P < 0.05), and in a subgroup of patients, beta thromboglobulin was reduced with successful treatment of hypertension with the ace inhibitor quinapril. we suggest that reversible platelet activation is present in hypertension. this may be a contributing factor to the link between this risk factor and the development of thrombotic disease such as stroke.

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  1. Department of Medicine, Haemostasis, Thrombosis and Vascular Biology Unit, The City Hospital, Dudley Road, Birmingham, B18 7QH, UK

    AD Blann, GYH Lip, IF Islim & DG Beevers

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  1. AD Blann
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  2. GYH Lip
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  3. IF Islim
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  4. DG Beevers
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Blann, A., Lip, G., Islim, I. et al. Evidence of platelet activation in hypertension. J Hum Hypertens 11, 607–609 (1997). https://doi.org/10.1038/sj.jhh.1000505

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  • DOI: https://doi.org/10.1038/sj.jhh.1000505

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