Abstract
Objective:
This study examined the association between body mass index (BMI) and waist circumference (WC) and coronary artery disease (CAD) in Taiwanese type 2 diabetic patients.
Methods:
A total of 1183 (558 men and 625 women) patients aged 62.4±11.6 years were studied. CAD was diagnosed by history or an electrocardiogram by Minnesota codes.
Results:
The respective cutoffs of BMI and WC as determined by the receiver operating characteristic curves were 24.5 kg/m2 and 90 cm for men, and 25 kg/m2 and 80 cm for women. Distributions of CAD prevalence and multivariate-adjusted odds ratio (MAOR) for BMI cutoffs of 24.5 and 25 kg/m2 were quite similar in men. MAOR for WC above the respective cutoffs for men and women was 1.832 (1.267–2.648) and 1.450 (0.956–2.200, 0.05<P<0.1), and for BMI⩾25 kg/m2 was 1.759 (1.213–2.551) and 1.471 (1.052–2.058) for men and women, respectively. Patients with BMI⩾25 kg/m2 and WC⩾90 cm for men or ⩾80 cm for women had the highest risk of CAD when compared to those without either risk factor, with respective MAOR of 2.053 (1.352–3.118) and 1.698 (1.071–2.691).
Conclusion:
The recommended BMI and WC cutoffs for obesity for Asian adults are associated with CAD in Taiwanese T2DM.
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Acknowledgements
This study was supported by grants from the Department of Health (DOH89-TD-1035) and the National Science Council (NSC-90-2320-B-002-197, NSC-92-2320-B-002-156 and NSC-93-2320-B-002-071), Taiwan.
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Tseng, CH. Body mass index and waist circumference as determinants of coronary artery disease in Taiwanese adults with type 2 diabetes mellitus. Int J Obes 30, 816–821 (2006). https://doi.org/10.1038/sj.ijo.0803218
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DOI: https://doi.org/10.1038/sj.ijo.0803218
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