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Relationships between physical activity, obesity and diabetes mellitus in a French elderly population: the POLA study

Abstract

OBJECTIVE: To analyse the relationships between body mass index, waist circumference, waist-to-hip ratio, physical activity and the risk of type 2 diabetes in a French elderly population.

DESIGN AND SUBJECTS: We conducted a cross-sectional study on 1113 men and 1419 women aged 60 y or more, participating in the POLA Study.

RESULTS: The prevalence of diabetes was two-fold higher in men than in women (19.1% and 9.3%, respectively). The anthropometric variables studied—body mass index (BMI), waist circumference (WC) and the waist/hip ratio (WHR)—were all positively related to the prevalence of type 2 diabetes. The strongest relationships were found for BMI in men and WHR in women. In both genders, sport activity and diabetes were inversely linked whereas no relationship was shown between the amount of household activity and diabetes mellitus.

CONCLUSION: In the elderly, overall obesity in men and abdominal fat accumulation in women appeared strongly related to diabetes. Sport activity was negatively and independently associated with the prevalence of diabetes mellitus.

International Journal of Obesity (2001) 25, 512–518

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References

  1. Kaye SA, Folsom AR, Sprafka JM, Prineas RJ, Wallace RB . Increased incidence of diabetes mellitus in relation to abdominal adiposity in older women J Clin Epidemiol 1991 44: 329–334.

    Article  CAS  Google Scholar 

  2. Chan JM, Rimm EB, Colditz GA, Stampfer MJ, Willett WC . Obesity, fat distribution, and weight gain as risk factors for clinical diabetes in men Diabetes Care 1994 17: 961–969.

    Article  CAS  Google Scholar 

  3. Albu J, Pi-Sunyer FX . Obesity and diabetes In: Bray GA, Bouchard C, James WPT (eds) Handbook of obesity Marcel Dekker: New York 1998 pp 697–707.

    Google Scholar 

  4. Qiao Q, Rajala U, Keinanen-Kiukaanniemi S . Hypertension, hyperinsulinaemia and obesity in middle-aged Finns with impaired glucose tolerance J Hum Hypertens 1998 12: 265–269.

    Article  CAS  Google Scholar 

  5. Bonner G . Hyperinsulinemia, insulin resistance, and hypertension J Cardiovasc Pharmac 1994 24 (Suppl 2): S39–S49.

    Article  Google Scholar 

  6. Bell PM . Clinical significance of insulin resistance Diabetes Med 1996 13: 504–509.

    Article  CAS  Google Scholar 

  7. French SA, Folsom AR, Jeffery RW, Zheng W, Mink PJ, Baxter JE . Weight variability and incident disease in older women: the Iowas Women's Health Study Int J Obes Relat Metab Disord 1997 21: 217–223.

    Article  CAS  Google Scholar 

  8. Yamashita S, Nakamura T, Shimomura I, Nishida M, Yoshida S, Kotani K, Kameda-Takemuara K, Tokunaga K, Matsuzawa Y . Insulin resistance and body fat distribution Diabetes Care 1996 19: 287–291.

    Article  CAS  Google Scholar 

  9. Manson JE, Willett WC, Stampfer MJ, Colditz GA, Hunter DJ, Hankinson SE, Hennekens CH, Speizer FE . Body weight and mortality among women New Engl J Med 1995 333: 677–685.

    Article  CAS  Google Scholar 

  10. Poehlman ET, Toth MJ, Bunyard LB, Gardner AW, Donaldson KE, Colman E, Fonong T, Ades PH . Physiological predictors of increasing total and central adiposity in aging men and women Arch Intern Med 1995 155: 2443–2448.

    Article  CAS  Google Scholar 

  11. Panotopoulos G, Raison J, Ruiz JC, Guy-Grand B, Basdevant A . Weight gain at the time of menopause Hum Reprod 1997 12 (Suppl 1): 26–33.

    Article  Google Scholar 

  12. Mulder M, Ranchor AV, Sanderman R, Bouma J, Vanderheuvel WJA . The stability of lifestyle behaviour Int J Epidemiol 1998 27: 199–207.

    Article  CAS  Google Scholar 

  13. Ivy JL . Role of exercise training in the prevention and treatment of insulin resistance and non-insulin-dependent diabetes mellitus Sports Med 1997 24: 321–336.

    Article  CAS  Google Scholar 

  14. Williamson DF, Madans J, Anda RF, Kleinman JC, Kahn HS, Byers T . Recreational physical activity and ten-year weight change in a US national cohort Int J Obes Relat Metab Disord 1993 17: 279–286.

    CAS  PubMed  Google Scholar 

  15. Shephard RJ . Physical activity, health, and well-being at different life stages Res Q Exerc Sport 1995 66: 298–302.

    Article  CAS  Google Scholar 

  16. Eriksson J, Taimela S, Koivisto VA . Exercise and the metabolic syndrome Diabetologia 1997 40: 125–135.

    Article  CAS  Google Scholar 

  17. Leon AS, Connett J . Physical activity and 10.5 y mortality in the Multiple Risk Factor Intervention Trial (MRFIT) Int J Epidemiol 1991 20: 690–697.

    Article  CAS  Google Scholar 

  18. Lacroix AZ, Leveille SG, Hecht JA, Grothaus LC, Wagner EH . Does walking decrease the risk of cardiovascular disease hospitalizations and death in older adults? J Am Geriat Soc 1996 44: 113–120.

    Article  CAS  Google Scholar 

  19. Delcourt C, Cristol JP, Tessier JF, Leger CL, Descomps B, Papoz L, and the POLA Study Group . Risk factors for cortical, nuclear and posterior subcapsular cataracts: the POLA Study Am J Epidemiol 2000 151: 497–504.

    Article  CAS  Google Scholar 

  20. The Expert Committee on the diagnosis and classification of diabetes mellitus. Report of the Expert Committee on the diagnosis and classification of diabetes mellitus Diabetes Care 1997 20: 1183–1197.

  21. Bourdel-Marchasson I, Dubroca B, Manciet G, Decamps A, Emeriau JP, Dartigues JF . Prevalence of diabetes and effect on quality of life in older French living in the community: the PAQUID Epidemiological Survey J Am Geriat Soc 1997 45: 295–301.

    Article  CAS  Google Scholar 

  22. Tauber JP, Courdy P, Ducimetiere P, Amouyel P, Arveiler D, Cottel D, Lamamy N, Bingham A, Ruidavets JB, Ferrieres J . Prevalence of type 2 diabetes, impaired fasting glucose and associated cardiovascular risk factors in a middle-aged French population: the MONICA Study 33rd Annual Meeting of the European Diabetes Epidemiology Study Group 16–19 May 1998, Vaux de Cernay, France

  23. Papoz L, Vauzelle F, Vexiau P, Cathelineau G . Pattern of treatment among diabetic patients in France Diabetes Care 1988 11: 586–591.

    Article  CAS  Google Scholar 

  24. Colvez GA, Eschwege E, Hatton F . Diabetes and private medicine Diabetes Metab 1983 9: 69–74.

    CAS  Google Scholar 

  25. Colditz GA, Willett WC, Stampfer MJ, Manson JE, Hennekens CH, Arky RA, Speizer FE . Weight as a risk factor for clinical diabetes in women Am J Epidemiol 1990 132: 501–513.

    Article  CAS  Google Scholar 

  26. Ledoux M, Lambert J, Reeder BA, Despres JP . A comparative analysis of weight to height and waist to hip circumference indices as indicators of the presence of cardiovascular disease risk factors. Canadian Heart Health Surveys Research Group CMAJ 1997 157 (Suppl 1): S32–S38.

    PubMed  Google Scholar 

  27. Kissebah AH . Intra-abdominal fat: is it a major factor in developing diabetes and coronary artery disease? Diabetes Res Clin Pract 1996 30 (Suppl): S25–S30.

    Article  Google Scholar 

  28. Rosmond R, Bjorntorp P . Psychosocial and socio-economic factors in women and their relationship to obesity and regional body fat distribution Int J Obes Relat Metab Disord 1999 23: 138–145.

    Article  CAS  Google Scholar 

  29. Ohlsson LO, Larsson B, Svardsudd K, Welin L, Eriksson H, Wilhelmsen L, Bjorntorp P, Tibblin G . The influence of body fat distribution on the incidence of diabetes mellitus. A 13.5 y of follow-up of the participants in the study of men born in 1913 Diabetes 1985 34: 1055–1058.

    Article  Google Scholar 

  30. Bjorntorp P . Abdominal fat distribution and disease: an overview of epidemiological data Ann Med 1992 24: 15–18.

    Article  CAS  Google Scholar 

  31. Pouliot MC, Despres JP, Nadeau A, Moorjani S, Prud'Homme D, Lupien PJ, Tremblay A, Bouchard C . Visceral obesity in men. Associations with glucose tolerance, plasma insulin, and lipoprotein levels Diabetes 1992 41: 826–834.

    Article  CAS  Google Scholar 

  32. Goodman-Gruen D, Barrett-Connor E . Sex differences in measures of body fat and body fat distribution in the elderly Am J Epidemiol 1996 143: 898–906.

    Article  CAS  Google Scholar 

  33. Seidell JC, Oosterlee A, Deurenberg P, Hautvast JG, Ruijs JH . Abdominal fat depots measured with computed tomography: effects of degree of obesity, sex, and age Eur J Clin Invest 1988 42: 805–815.

    CAS  Google Scholar 

  34. Molarius A, Seidell JC, Sans S, Tuomilehto J, Kuulasmaa K, For The WHO MONICA Project . Waist and hip circumferences, and waist-hip ratio in 19 populations of the WHO MONICA Project Int J Obes Relat Metab Disord 1999 23: 116–125.

    Article  CAS  Google Scholar 

  35. Han TS, Feskens EJM, Lean MEJ, Seidell JC . Associations of body composition with type 2 diabetes mellitus Diabetic Med 1998 15: 129–135.

    Article  CAS  Google Scholar 

  36. Lynch J, Helmrich SP, Lakka TA, Kaplan GA, Cohen RD, Salonen R, Salonen JT . Moderately intense physical activities and high levels of cardiorespiratory fitness reduce the risk of non-insulin-dependent diabetes mellitus in middle-aged men Arch Intern Med 1996 156: 1307–1314.

    Article  CAS  Google Scholar 

  37. Helmrich SP, Ragland DR, Leung RW, Paffenbarger RS Jr . Physical activity and reduced occurrence of non-insulin-dependent diabetes mellitus New Engl J Med 1991 325: 147–152.

    Article  CAS  Google Scholar 

  38. Manson JE, Rimm EB, Stampfer MR, Colditz GA, Willett WC, Krolewski AS, Rosner B, Hennekens CH, Speizer FE . Physical activity and incidence of non-insulin-dependent diabetes mellitus in women Lancet 1991 ii: 774–778.

    Article  Google Scholar 

  39. Wallberg-Henriksson H, Rincon J, Zierath JR . Exercise in the management of non-insulin-dependent diabetes mellitus Sports Med 1998 25: 25–35.

    Article  CAS  Google Scholar 

  40. Mayerdavis EJ, Dagostino R, Karter AJ, Haffner SM, Rewers MJ, Saad M, Bergman RN . Intensity and amount of physical activity in relation to insulin sensitivity: the Insulin Resistance Atherosclerosis Study JAMA 1998 279: 669–674.

    Article  CAS  Google Scholar 

  41. Gurwitz JH, Field TS, Glynn RJ, Manson JE, Avorn J, Taylor JO, Hennekens CH . Risk factors for non-insulin-dependent diabetes mellitus requiring treatment in the elderly J Am Geriat Soc 1994 42: 1235–1240.

    Article  CAS  Google Scholar 

  42. Pols MA, Peeters PHM, Twisk JWR, Kemper HCG, Grobbee DE . Physical activity and cardiovascular risk profile in women Am J Epidemiol 1997 146: 322–328.

    Article  CAS  Google Scholar 

  43. Pols MA, Peeters PHM, Kemper HCG, Grobbee DE . Methodological aspects of physical activity assessment in epidemiological studies Eur J Epidemiol 1998 14: 63–70.

    Article  CAS  Google Scholar 

  44. Elward K, Larson EB . Benefits of exercise for older adults. A review of existing evidence and current recommendations for the general population Clin Geriat Med 1992 8: 35–50.

    Article  CAS  Google Scholar 

  45. Crespo CJ, Keteyian SJ, Health GW, Sempos CT . Leisure-time physical activity among US adults. Results from the Third National Health and Nutritional Examination Survey Arch Intern Med 1996 156: 93–98.

    Article  CAS  Google Scholar 

  46. Kohrt WM, Obert KA, Holloszy JO . Exercise training improves fat distribution patterns in 60- to 70-year-old men and women J Gerontol A Biol Sci Med Sci 1992 47: M99–M105.

    Article  CAS  Google Scholar 

  47. Schwartz RS, Shuman WP, Larson V, Cain KC, Fellingham GW, Béard JC, Khan SE, Stratton JR, Cerqueira MD, Abrass IB . The effect of intensive endurance exercise training on body fat distribution in young and older men Metabolism 1991 40: 545–551.

    Article  CAS  Google Scholar 

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Acknowledgements

The POLA study is supported by the Institut National de la Santé et de la Recherche Médicale, by grants from the Fondation de France, Department of Epidemiology of Ageing, by financial support from Rhône-Poulenc, Essilor, and CERIN, by grants from the Fondation pour la Recherche Médicale, the Région Languedoc-Roussillon and the Association Retina-France.

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Defay, R., Delcourt, C., Ranvier, M. et al. Relationships between physical activity, obesity and diabetes mellitus in a French elderly population: the POLA study. Int J Obes 25, 512–518 (2001). https://doi.org/10.1038/sj.ijo.0801570

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