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| Open Access(+)-Usnic acid and its salts, inhibitors of SARS‐CoV‐2, identified by using in silico methods and in vitro assay
- Eunseok Oh
- , Weihong Wang
- & Heonjoong Kang
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| Open AccessKOPI: Kinase inhibitOr Proteome Impact analysis
- Ginny Xiaohe Li
- , Tianyun Zhao
- & Radoslaw M. Sobota
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| Open AccessNovel compound shows in vivo anthelmintic activity in gerbils and sheep infected by Haemonchus contortus
- Elora Valderas-García
- , Nerea Escala
- & Rafael Balaña-Fouce
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| Open AccessPharmacological sequestration of mitochondrial calcium uptake protects against dementia and β-amyloid neurotoxicity
- Elena F. Shevtsova
- , Plamena R. Angelova
- & Andrey Y. Abramov
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| Open AccessPregabalin administration in patients with fibromyalgia: a Bayesian network meta-analysis
- Filippo Migliorini
- , Nicola Maffulli
- & Giorgia Colarossi
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| Open AccessIn silico screening of some compounds derived from the desert medicinal plant Rhazya stricta for the potential treatment of COVID-19
- Nabih A. Baeshen
- , Abdulaziz O. Albeshri
- & Mohammed N. Baeshen
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| Open AccessQuercetin and luteolin are single-digit micromolar inhibitors of the SARS-CoV-2 RNA-dependent RNA polymerase
- Federico Munafò
- , Elisa Donati
- & Marco De Vivo
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| Open AccessLabel-free morphological sub-population cytometry for sensitive phenotypic screening of heterogenous neural disease model cells
- Yuta Imai
- , Madoka Iida
- & Ryuji Kato
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| Open AccessExamination of diverse iron-chelating agents for the protection of differentiated PC12 cells against oxidative injury induced by 6-hydroxydopamine and dopamine
- Pavlína Hašková
- , Lenka Applová
- & Tomáš Šimůnek
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| Open AccessStructure-based assessment and druggability classification of protein–protein interaction sites
- Lara Alzyoud
- , Richard A. Bryce
- & Mohammad A. Ghattas
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| Open AccessApigeninidin-rich Sorghum bicolor (L. Moench) extracts suppress A549 cells proliferation and ameliorate toxicity of aflatoxin B1-mediated liver and kidney derangement in rats
- Solomon E. Owumi
- , Abisola I. Kazeem
- & Adegboyega K. Oyelere
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| Open AccessEfficacy of 0.01% low dose atropine and its correlation with various factors in myopia control in the Indian population
- Shweta Chaurasia
- , Seema Negi
- & Mangat Ram Dogra
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| Open AccessAsteltoxin inhibits extracellular vesicle production through AMPK/mTOR-mediated activation of lysosome function
- Fumie Mitani
- , Jianyu Lin
- & Chitose Oneyama
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| Open AccessA combination screening to identify enhancers of para-aminosalicylic acid against Mycobacterium tuberculosis
- Jinyeong Heo
- , Dahae Koh
- & Vincent Delorme
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| Open AccessNU-9 improves health of hSOD1G93A mouse upper motor neurons in vitro, especially in combination with riluzole or edaravone
- Barış Genç
- , Mukesh Gautam
- & P. Hande Ozdinler
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| Open AccessMetabolomics-based profiling of 4 avocado varieties using HPLC–MS/MS and GC/MS and evaluation of their antidiabetic activity
- Inas Y. Younis
- , Amira R. Khattab
- & Mahitab H. El Bishbishy
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| Open AccessInhibition of the hexamerization of SARS-CoV-2 endoribonuclease and modeling of RNA structures bound to the hexamer
- Duy Phuoc Tran
- , Yuta Taira
- & Akio Kitao
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| Open AccessDiscovery of antimicrobials by massively parallelized growth assays (Mex)
- Philipp Koch
- , Steven Schmitt
- & Martin Held
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| Open AccessMetabolites of soil microorganisms modulate amyloid β production in Alzheimer’s neurons
- Takayuki Kondo
- , Tsuyoshi Yamamoto
- & Haruhisa Inoue
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| Open AccessA functional screen with metformin identifies microRNAs that regulate metabolism in colorectal cancer cells
- Ayla Orang
- , Saira R. Ali
- & Michael Z. Michael
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| Open AccessClass imbalance learning with Bayesian optimization applied in drug discovery
- Shenmin Guan
- & Ning Fu
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| Open AccessOne-step visualization of natural cell activities in non-labeled living spheroids
- Shotaro Tanaka
- , Kotaro Takizawa
- & Fumio Nakamura
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| Open AccessPotential antitumor and anti-inflammatory activities of an extracellular polymeric substance (EPS) from Bacillus subtilis isolated from a housefly
- Lingxiu Zhang
- & Huilan Yi
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| Open AccessGLUT3 inhibitor discovery through in silico ligand screening and in vivo validation in eukaryotic expression systems
- Cristina V. Iancu
- , Giovanni Bocci
- & Jun-yong Choe
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| Open AccessA cell-based phenotypic library selection and screening approach for the de novo discovery of novel functional chimeric antigen receptors
- Julie K. Fierle
- , Johan Abram-Saliba
- & Steven M. Dunn
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| Open AccessIntegration of a miniaturized DMMB assay with high-throughput screening for identifying regulators of proteoglycan metabolism
- Yi Sun
- , Yuen-kee Tsui
- & Victor Leung
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| Open AccessTwo-step screening method to identify α-synuclein aggregation inhibitors for Parkinson’s disease
- Makoto Hideshima
- , Yasuyoshi Kimura
- & Kensuke Ikenaka
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| Open AccessDetermination of tyrosinase-cyanidin-3-O-glucoside and (−/+)-catechin binding modes reveal mechanistic differences in tyrosinase inhibition
- Kyung Eun Lee
- , Shiv Bharadwaj
- & Sang Gu Kang
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| Open AccessThe utilization of Blaptica dubia cockroaches as an in vivo model to test antibiotic efficacy
- Elliot Collins
- , Caleb Martin
- & Joseph Horzempa
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| Open AccessDrug repurposing for COVID-19 using graph neural network and harmonizing multiple evidence
- Kanglin Hsieh
- , Yinyin Wang
- & Yejin Kim
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| Open AccessA 3D primary human cell-based in vitro model of non-alcoholic steatohepatitis for efficacy testing of clinical drug candidates
- Simon Ströbel
- , Radina Kostadinova
- & Eva Thoma
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| Open AccessInhibitors of Mycobacterium tuberculosis EgtD target both substrate binding sites to limit hercynine production
- Thanuja D. Sudasinghe
- , Michael T. Banco
- & Donald R. Ronning
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| Open AccessDrug repurposing for coronavirus (SARS-CoV-2) based on gene co-expression network analysis
- Habib MotieGhader
- , Esmaeil Safavi
- & Roya asl Iranifam
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| Open AccessThe transcriptome of Balamuthia mandrillaris trophozoites for structure-guided drug design
- Isabelle Q. Phan
- , Christopher A. Rice
- & Peter J. Myler
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| Open AccessEstablishment of high-throughput screening HTRF assay for identification small molecule inhibitors of Skp2-Cks1
- Kaizhao Hu
- , Xiao-Jing Li
- & Hong-Min Liu
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| Open AccessPrediction of severe adverse events, modes of action and drug treatments for COVID-19’s complications
- Courtney Astore
- , Hongyi Zhou
- & Jeffrey Skolnick
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| Open AccessRepurposing diphenylbutylpiperidine-class antipsychotic drugs for host-directed therapy of Mycobacterium tuberculosis and Salmonella enterica infections
- M. T. Heemskerk
- , C. J. Korbee
- & M. C. Haks
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| Open AccessDevelopment of CIDEA reporter mouse model and its application for screening thermogenic drugs
- Yeonho Son
- , Cheoljun Choi
- & Yun-Hee Lee
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| Open AccessMitochondria-affecting small molecules ameliorate proteostasis defects associated with neurodegenerative diseases
- Elissa Tjahjono
- , Jingqi Pei
- & Natalia V. Kirienko
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| Open AccessA computational study of cooperative binding to multiple SARS-CoV-2 proteins
- Jianing Li
- , Kyle T. McKay
- & Severin T. Schneebeli
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| Open AccessBioactive recombinant human oncostatin M for NMR-based screening in drug discovery
- Olga A. Mass
- , Joseph Tuccinardi
- & Lisa R. Warner
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| Open AccessA proteomic platform to identify off-target proteins associated with therapeutic modalities that induce protein degradation or gene silencing
- Xin Liu
- , Ye Zhang
- & Fan Fan
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| Open AccessA phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation
- Sohaib Nizami
- , Val Millar
- & Elena Di Daniel
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| Open AccessIdentification of new GLUT2-selective inhibitors through in silico ligand screening and validation in eukaryotic expression systems
- Sina Schmidl
- , Oleg Ursu
- & Jun-yong Choe
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| Open AccessIdentification of small compounds regulating the secretion of extracellular vesicles via a TIM4-affinity ELISA
- Yunfei Ma
- , Takeshi Yoshida
- & Rikinari Hanayama
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| Open AccessReporter cell assay for human CD33 validated by specific antibodies and human iPSC-derived microglia
- Jannis Wißfeld
- , Mona Mathews
- & Harald Neumann
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| Open AccessBispecific repurposed medicines targeting the viral and immunological arms of COVID-19
- Martin A. Redhead
- , C. David Owen
- & Martin A. Walsh
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| Open AccessSelective control of the contact and transport between droplet pairs by electrowetting-on-dielectric for droplet-array sandwiching technology
- Satoshi Konishi
- , Chikara Ohya
- & Tatsuhiro Yamada
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| Open AccessLabel-free high-throughput screening assay for the identification of norepinephrine transporter (NET/SLC6A2) inhibitors
- Hubert J. Sijben
- , Wieke M. van Oostveen
- & Laura H. Heitman