Research articles

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  • A modular quantum system-on-chip architecture integrates thousands of individually addressable spin qubits in two-dimensional quantum microchiplet arrays into an integrated circuit designed for cryogenic control, supporting full connectivity for quantum memory arrays across spin–photon channels.

    • Linsen Li
    • Lorenzo De Santis
    • Dirk Englund
    Article
  • Assessment of surface contamination shows that trace oxygen is a key factor influencing the trajectory and quality of graphene grown by low-pressure chemical vapour deposition, with oxygen-free synthesis showing increased reproducibility and quality.

    • Jacob Amontree
    • Xingzhou Yan
    • James Hone
    Article
  • Reference assemblies of great ape sex chromosomes show that Y chromosomes are more variable in size and sequence than X chromosomes and provide a resource for studies on human evolution and conservation genetics of non-human apes.

    • Kateryna D. Makova
    • Brandon D. Pickett
    • Adam M. Phillippy
    ArticleOpen Access
  • Analysis of streamflow measurements from 1950 to 2020 across 3,049 snow-affected catchments over the Northern Hemisphere shows that seasonal streamflow occurs earlier in snow-heavy catchments but later in less snowy regions.

    • Juntai Han
    • Ziwei Liu
    • Yuting Yang
    Article
  • We develop a method for high-density vertical stacking of active-device multi-layers, implementing memory and logic functions, using unique VIP-FETs where a van der Waals intercalation layer modulates the p- or n-type nature of the FETs.

    • Yimeng Guo
    • Jiangxu Li
    • Zheng Han
    ArticleOpen Access
  • Inspired by the human visual system, a vision chip with primitive-based complementary pathways is developed to overcome the power and bandwidth wall of vision systems, achieving fast, precise, robust and high-dynamic-range sensing efficiently in the open world.

    • Zheyu Yang
    • Taoyi Wang
    • Luping Shi
    Article
  • A study presents a method to mitigate emissions of nitrous oxide from farmland using bacteria to consume nitrous oxide in soil with organic waste as a substrate and vector.

    • Elisabeth G. Hiis
    • Silas H. W. Vick
    • Lars R. Bakken
    ArticleOpen Access
  • Cryo-electron microscopy structures of the prime editor bound to a prime editing guide RNA and target DNA, in the pre-initiation, initiation and elongation and termination states, provide insights into the mechanism by which prime editing occurs.

    • Yutaro Shuto
    • Ryoya Nakagawa
    • Osamu Nureki
    ArticleOpen Access
  • Lolamicin, a novel antibiotic developed from a pyridinepyrazole precursor, exhibits potent activity against a broad range of Gram-negative multidrug-resistant clinical isolates, and good efficacy in mouse models of infection without inducing gut dysbiosis.

    • Kristen A. Muñoz
    • Rebecca J. Ulrich
    • Paul J. Hergenrother
    Article
  • Multilayer composites of 2D nanomaterials manufactured using a layer-by-layer methodology demonstrates strong polarization rotation, mechanical robustness and operational temperatures as high as 250 °C, despite being nano-achiral and partially disordered.

    • Jun Lu
    • Wenbing Wu
    • Nicholas A. Kotov
    Article
  • Comprehensive analyses of Cas9 proteins shed light on the evolution of the CRISPR–Cas9 system, and identify a pro-CRISPR accessory protein in bacteria that boosts CRISPR-mediated immunity by enhancing the DNA binding and cleavage activity of Cas9.

    • Shouyue Zhang
    • Ao Sun
    • Jun-Jie Gogo Liu
    Article
  • Observations from the Lucy spacecraft of the small main-belt asteroid (152830) Dinkinesh reveals unexpected complexity, with a longitudinal trough and equatorial ridge, as well as the discovery of the first contact binary satellite.

    • Harold F. Levison
    • Simone Marchi
    • Yifan Zhao
    ArticleOpen Access
  • Deformation of soft colloidal crystals lead to work hardening, similar to that seen in the deformation of metals.

    • Seongsoo Kim
    • Ilya Svetlizky
    • Frans Spaepen
    ArticleOpen Access