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Review Article |
Genetics of coronary artery disease: discovery, biology and clinical translation
The past decade has seen tremendous progress in understanding the genetic architecture of coronary artery disease (CAD). Khera and Kathiresan review research efforts that have improved our understanding of the genetic drivers of CAD, and discuss the promises and challenges of integrating genetic information into routine clinical practice.
- Amit V. Khera
- & Sekar Kathiresan
Genome editing for disease locus dissection
Human genome editing in heart disease
From non-coding risk variant to biological mechanism in CAD