The detection of mobile genetic elements is crucial for exploring the ecology and evolution of microbial communities, and it has diverse implications in biotechnology and public health. geNomad is a computational framework that enables researchers to precisely identifiy and annotate plasmids and viruses in sequencing data on a large scale.
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References
Koonin, E. V. Viruses and mobile elements as drivers of evolutionary transitions. Phil. Trans. R. Soc. B 371, 20150442 (2016). A review that discusses how MGEs function as genetic reservoirs that allow major evolutionary transitions.
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This is a summary of: Camargo, A. P. et al. Identification of mobile genetic elements with geNomad. Nat. Biotechnol. https://doi.org/10.1038/s41587-023-01953-y (2023).
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Fast and accurate identification of plasmids and viruses in sequencing data using geNomad. Nat Biotechnol (2023). https://doi.org/10.1038/s41587-023-01982-7
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DOI: https://doi.org/10.1038/s41587-023-01982-7
