Liquid droplets form in cells to concentrate specific biomolecules (while excluding others) in order to perform specific functions. The molecular mechanisms that determine whether different macromolecules undergo co-partitioning or exclusion has so far remained elusive. Now, two studies uncover key principles underlying this selectivity.
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Phillips, M., Ghosh, K. Rules of selective condensation in cells. Nat. Chem. (2024). https://doi.org/10.1038/s41557-024-01525-w
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DOI: https://doi.org/10.1038/s41557-024-01525-w