Models like ChatGPT and DALL-E2 generate text and images in response to a text prompt. Despite different data and goals, how can generative models be useful for protein engineering?
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Acknowledgements
We thank A. Busia, H. Jiang, M. Lukarska, H. Nisonoff, Y. Song and J. Xiong for discussions and feedback.
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J.L. consults for Fable Tx and Inscripta. C.H. is a cofounder of Escalante Bio. The remaining authors declare no competing interests.
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Hsu, C., Fannjiang, C. & Listgarten, J. Generative models for protein structures and sequences. Nat Biotechnol 42, 196–199 (2024). https://doi.org/10.1038/s41587-023-02115-w
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DOI: https://doi.org/10.1038/s41587-023-02115-w
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