Chromosomal profiles of DNA methylation in colon cancer cells
Methylation profile in primary fibroblasts (red) and SW48 cancer cells (green) over a 10-Mb window on chromosome 3q. The RefSeq gene annotations below the graph illustrate that the region of extensive hypomethylation in SW48 cells coincides with a gene-poor domain.
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Identical twins often develop different characteristics, even though they carry the same sequence of DNA nucleotides. How can this be? The answer lies in epigenomics.
