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A human metaphase plate, from the original Tjio and Levan paper, showing 46 chromosomes.

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A human metaphase plate, from the original Tjio and Levan paper, showing 46 chromosomes.
A human metaphase plate, from the original Tjio and Levan paper, showing 46 chromosomes.

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Cytologists had been studying chromosome behavior since the late 19th century. Why did it take until 1956 to figure out the correct human chromosome number, thanks to Joe Hin Tjio and Albert Levan?
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