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Systems virology is the scientific discipline that integrates high-throughput molecular techniques and computational tools to study all aspects of viruses and viral diseases, in an effort to increase our understanding of viral pathogenesis and to improve diagnostics and therapeutics of viral diseases.
A diverse range of viruses of the yak gut in Qinghai-Tibet Plateau is presented, showing significant sequence identity across regions. Also regional differences in gene function and significant virus-bacterium symbiotic networks were uncovered.
The diversity and impact of viruses in remote marine environments are less well understood. In this study, the authors analyse an -omics dataset to gain insights into the genomics and potential role of endemic viruses infecting ecologically important microbes inhabiting the ocean cavity beneath the Ross Ice Shelf.
A pseudotime analysis of the host cell response to SARS-CoV-2 infection using publicly available scRNA-seq data derived from in vitro studies reveals a non-lineal, triphasic transcriptional response and suggests a global regulatory mechanism.
This month's Genome Watch highlights a new large-scale serological platform for the simultaneous detection of multiple human viruses in a single drop of blood.
