Tumour virus infections articles from across Nature Portfolio

Tumour virus infections are caused by oncogenic DNA or RNA viruses. They can cause cancer by two different processes: directly through the expression of viral proteins that disrupt tissue cells and result in their transformation; and indirectly through mutation of the host cell DNA through viral integration (also known as insertional mutagenesis).

Latest Research and Reviews

Research
15 March 2023 | Open Access

Differences in HPV-specific antibody Fc-effector functions following Gardasil® and Cervarix® vaccination
- Vicky Roy
- , Wonyeong Jung
- & Galit Alter
npj Vaccines 8, 39
Research
10 February 2023 | Open Access

O-GlcNAcylation of YTHDF2 promotes HBV-related hepatocellular carcinoma progression in an N⁶-methyladenosine-dependent manner
- Yang Yang
- , Yu Yan
- & Ailong Huang
Signal Transduction and Targeted Therapy 8, 63
Research
24 January 2023 | Open Access

Phosphorylation of UHRF2 affects malignant phenotypes of HCC and HBV replication by blocking DHX9 ubiquitylation
- Kejia Wu
- , Yiqi Zhang
- & Changzhu Duan
Cell Death Discovery 9, 27
Research | 12 January 2023

Hepatitis B virus X protein promotes MAN1B1 expression by enhancing stability of GRP78 via TRIM25 to facilitate hepatocarcinogenesis
- Hongjuan You
- , Ning Zhang
- & Renxian Tang
British Journal of Cancer 128, 992-1004
Research
19 December 2022 | Open Access

Repeated dosing improves oncolytic rhabdovirus therapy in mice via interactions with intravascular monocytes

A secondary (but not primary) dose of the oncolytic virus, VSV, is captured by monocytes and promotes CD8 + T cell recruitment, thereby revealing a mechanism underlying the clinical benefit of repeat dosing in oncolytic virus therapy.
- Victor Naumenko
- , Jahanara Rajwani
- & Craig N. Jenne
Communications Biology 5, 1385
Research
10 October 2022 | Open Access

Human papillomavirus integration perspective in small cell cervical carcinoma

Small cell cervical carcinoma (SCCC) is a rare but aggressive malignancy. Here, the authors report human papillomavirus features and genomic landscape in SCCC via high-throughput sequencing methods and identify MYC, SOX, NR4A, ANKRD and CEA family genes as HPV-integrated hotspots.
- Xiaoli Wang
- , Wenlong Jia
- & Shuang Li
Nature Communications 13, 5968

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News and Comment

News & Views | 15 December 2022

The gut–liver axis in HCV infection

Longitudinal sampling of patients with hepatitis C virus before and after elimination of the virus reveals links between functions of the gut microbiome and liver disease.
- Kira L. Newman
- & Nobuhiko Kamada
Nature Microbiology 8, 6-7
Comments & Opinion | 30 December 2021

Cancer therapy with decreased SARS-CoV-2 infection rates in cancer patients
- Takuma Hayashi
- & Ikuo Konishi
British Journal of Cancer 126, 521-522
Correspondence | 29 April 2021

The HTLV-1 proviral status is a potential prognostic biomarker for adult T-cell leukemia-lymphoma treated with allogeneic stem cell transplantation
- Kosuke Toyoda
- , Jun-ichirou Yasunaga
- & Masao Matsuoka
Bone Marrow Transplantation 56, 2027-2030
Correspondence
01 February 2021 | Open Access

XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53-mediated caspase-dependent apoptosis
- Eline Boons
- , Tatiane C. Nogueira
- & Dirk Daelemans
Blood Cancer Journal 11, 27
News & Views | 09 October 2020

A global effort to understand the riddles of COVID-19 and cancer

Cancer has found a formidable foil in COVID-19, and this has brought to the fore the early concerns that COVID-19 could have a deeper impact on oncology patients. Two studies now provide insights into the enigma surrounding the determinants of the worsening of COVID-19 symptoms in patients with cancer.
- Vivek Subbiah
Nature Cancer 1, 943-945
Research Highlights | 06 August 2019

Virus-mediated hijack of one-carbon metabolism

Wang et al. investigated the early metabolic changes associated with Epstein–Barr virus (EBV) infection of B cells, which may have implications for EBV-driven lymphomas.
- Maria Giuseppina Baratta
Nature Reviews Cancer 19, 486

All News & Comment

Tumour virus infections articles from across Nature Portfolio

Latest Research and Reviews

Differences in HPV-specific antibody Fc-effector functions following Gardasil® and Cervarix® vaccination

O-GlcNAcylation of YTHDF2 promotes HBV-related hepatocellular carcinoma progression in an N⁶-methyladenosine-dependent manner

Phosphorylation of UHRF2 affects malignant phenotypes of HCC and HBV replication by blocking DHX9 ubiquitylation

Hepatitis B virus X protein promotes MAN1B1 expression by enhancing stability of GRP78 via TRIM25 to facilitate hepatocarcinogenesis

Repeated dosing improves oncolytic rhabdovirus therapy in mice via interactions with intravascular monocytes

Human papillomavirus integration perspective in small cell cervical carcinoma

News and Comment

The gut–liver axis in HCV infection

Cancer therapy with decreased SARS-CoV-2 infection rates in cancer patients

The HTLV-1 proviral status is a potential prognostic biomarker for adult T-cell leukemia-lymphoma treated with allogeneic stem cell transplantation

XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53-mediated caspase-dependent apoptosis

A global effort to understand the riddles of COVID-19 and cancer

Virus-mediated hijack of one-carbon metabolism

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