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| Open AccessHepa-ToxMOA: a pathway-screening method for evaluating cellular stress and hepatic metabolic-dependent toxicity of natural products
- Se-Myo Park
- , Mi-Sun Choi
- & Jung-Hwa Oh
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| Open AccessKaempferol mitigates reproductive dysfunctions induced by Naja nigricollis venom through antioxidant system and anti-inflammatory response in male rats
- Akindele Oluwatosin Adeyi
- , Babafemi Siji Ajisebiola
- & Olukunle Silas Fagbenro
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| Open AccessIntegrating transcriptomics and metabolomics to elucidate the mechanism by which taurine protects against DOX-induced depression
- Yanan Li
- , Luxi Li
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| Open AccessSafety evaluation of PEGylated MNPs and p-PEGylated MNPs in SD rats
- Hairuo Wen
- , Guitao Huo
- & Shujie Liu
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| Open AccessLower cardiotoxicity of CPX-351 relative to daunorubicin plus cytarabine free-drug combination in hiPSC-derived cardiomyocytes in vitro
- Marie C. Fortin
- , Andrew S. LaCroix
- & Dino Manca
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| Open AccessCharacterization of cannabinoid plasma concentration, maternal health, and cytokine levels in a rat model of prenatal Cannabis smoke exposure
- Tallan Black
- , Sarah L. Baccetto
- & Robert B. Laprairie
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| Open AccessIncidence of rhabdomyolysis occurrence in psychoactive substances intoxication: a systematic review and meta-analysis
- Alireza Amanollahi
- , Tannaz Babeveynezhad
- & Yadollah Mehrabi
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| Open AccessImmunomodulatory effects of nanoparticles on dendritic cells in a model of allergic contact dermatitis: importance of PD-L2 expression
- Angela Wong Lau
- , Jessica Perez Pineda
- & Lisa A. DeLouise
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| Open AccessTrends and practices following the 2016 hydroxychloroquine screening guidelines
- Fritz Gerald P. Kalaw
- , Justin Arnett
- & Shyamanga Borooah
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| Open AccessCSL-Tox: an open-source analytical framework for the comparison of short-term and long-term toxicity end points and assessing the need of chronic studies in drug development
- Doha Naga
- , Smaragda Dimitrakopoulou
- & Eunice Musvasva
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| Open AccessEvaluation of drug-induced liver toxicity of trovafloxacin and levofloxacin in a human microphysiological liver model
- Tim Kaden
- , Katja Graf
- & Martin Raasch
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| Open AccessMolecular basis of GDF15 induction and suppression by drugs in cardiomyocytes and cancer cells toward precision medicine
- Lisa-Maria Winter
- , Diana Reinhardt
- & Seong-Wook Yun
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| Open AccessForensic toxicokinetics of difenidol hydrochloride in vivo verified by practical lethal cases
- Weifen Niu
- , Tongxi Ren
- & Keming Yun
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| Open AccessPharmacokinetics, biodistribution and toxicology of novel cell-penetrating peptides
- L. Reveret
- , M. Leclerc
- & F. Calon
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| Open AccessIn vivo toxicity evaluation of a polyoxotungstate nanocluster as a promising contrast agent for computed tomography
- Marko Stojanović
- , Jovana Lalatović
- & Danijela Krstić
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| Open AccessThe effect of Alnus incana (L.) Moench extracts in ameliorating iron overload-induced hepatotoxicity in male albino rats
- Fatma Abo-Elghiet
- , Shaza A. Mohamed
- & Samah Fathy Ahmed
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| Open AccessCannaCount: an improved metric for quantifying estimates of maximum possible cannabinoid exposure
- Ashley M. Lambros
- , Kelly A. Sagar
- & Staci A. Gruber
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| Open AccessAsperuloside attenuates cadmium-induced toxicity by inhibiting oxidative stress, inflammation, fibrosis and apoptosis in rats
- Zhiyang Kong
- , Chunhong Liu
- & Opeyemi Joshua Olatunji
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| Open AccessAccurate clinical toxicity prediction using multi-task deep neural nets and contrastive molecular explanations
- Bhanushee Sharma
- , Vijil Chenthamarakshan
- & Payel Das
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| Open AccessA low-cost smartphone fluorescence microscope for research, life science education, and STEM outreach
- Madison A. Schaefer
- , Heather N. Nelson
- & Jacob H. Hines
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| Open AccessPreparing pathological data to develop an artificial intelligence model in the nonclinical study
- Ji-Hee Hwang
- , Minyoung Lim
- & Jae-Woo Cho
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| Open AccessA comparative study of postmortem distribution and postmortem diffusion of tramadol in rabbits
- Hongliang Su
- , Lingxiao Wang
- & Keming Yun
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| Open AccessSynergy of ruthenium metallo-intercalator, [Ru(dppz)2(PIP)]2+, with PARP inhibitor Olaparib in non-small cell lung cancer cells
- Nur Aininie Yusoh
- , Suet Lin Chia
- & Martin R. Gill
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| Open AccessComparative proteoinformatics revealed the essentials of SDS impact on HaCaT keratinocytes
- Timur Shkrigunov
- , Yulia Kisrieva
- & Natalia Petushkova
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| Open AccessAn efficient human stem cells derived cardiotoxicity testing platform for testing oncotherapeutic analogues of quercetin and cinnamic acid
- Saurabh Mandal
- , Naisarg Gamit
- & Sudha Warrier
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| Open AccessComparative study of the cytotoxicity, apoptotic, and epigenetic effects of Boswellic acid derivatives on breast cancer
- Fatemeh Jamshidi-adegani
- , Shokoofeh Ghaemi
- & Ahmed Al-Harrasi
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| Open AccessToxicology evaluation of overdose hydroxychloroquine on zebrafish (Danio rerio) embryos
- Min Luo
- , Dan Xie
- & Yanyan Liu
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| Open AccessCharacterizing the metabolic effects of the selective inhibition of gut microbial β-glucuronidases in mice
- Marine P. M. Letertre
- , Aadra P. Bhatt
- & Jonathan R. Swann
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| Open AccessBee-safe peptidomimetic acaricides achieved by comparative genomics
- Vikas Jindal
- , Daqi Li
- & Yoonseong Park
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| Open AccessContact exposure to neonicotinoid insecticides temporarily suppresses the locomotor activity of Pardosa lugubris agrobiont wolf spiders
- Milan Řezáč
- , Gabriela Přibáňová
- & Petr Heneberg
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| Open AccessInhibitory effects of Serjania erecta on the development of Chrysodeixis includens
- Samylla Tassia Ferreira de Freitas
- , Agna Rita dos Santos Rodrigues
- & Fábio Henrique Dyszy
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| Open AccessA novel differentiated HuH-7 cell model to examine bile acid metabolism, transport and cholestatic hepatotoxicity
- Chitra Saran
- , Dong Fu
- & Kim L. R. Brouwer
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| Open AccessFunctional human cell-based vascularised cardiac tissue model for biomedical research and testing
- Maria Koivisto
- , Tuomas A. Tolvanen
- & Tuula Heinonen
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| Open AccessCurcumin piperidone derivatives induce anti-proliferative and anti-migratory effects in LN-18 human glioblastoma cells
- Nur Syahirah Che Razali
- , Kok Wai Lam
- & Kok Meng Chan
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| Open AccessPotentilla chinensis aqueous extract attenuates cyclophosphamide-induced hemorrhagic cystitis in rat model
- Kajetan Juszczak
- , Jan Adamowicz
- & Andrzej Wróbel
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| Open AccessGrape seed proanthocyanidin extract inhibits DNA and protein damage and labile iron, enzyme, and cancer cell activities
- Hosam M. Habib
- , Esmail M. El-Fakharany
- & Wissam H. Ibrahim
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| Open AccessEfficacy and safety of ketone ester infusion to prevent muscle weakness in a mouse model of sepsis-induced critical illness
- Ruben Weckx
- , Chloë Goossens
- & Lies Langouche
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| Open AccessCoplanar embedding of multiple 3D cell models in hydrogel towards high-throughput micro-histology
- Sarah Heub
- , Fatemeh Navaee
- & Gilles Weder
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| Open AccessTranscriptional changes of biochemical pathways in Meloidogyne incognita in response to non-fumigant nematicides
- Catherine L. Wram
- , Cedar N. Hesse
- & Inga A. Zasada
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| Open AccessTranscriptional response of Meloidogyne incognita to non-fumigant nematicides
- Catherine L. Wram
- , Cedar N. Hesse
- & Inga A. Zasada
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| Open AccessExamination of diverse iron-chelating agents for the protection of differentiated PC12 cells against oxidative injury induced by 6-hydroxydopamine and dopamine
- Pavlína Hašková
- , Lenka Applová
- & Tomáš Šimůnek
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| Open AccessThe K-Ras(G12D)-inhibitory peptide KS-58 suppresses growth of murine CT26 colorectal cancer cell-derived tumors
- Kotaro Sakamoto
- , Bangzhong Lin
- & Shinsaku Nakagawa
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| Open AccessSimple, fast and reliable CE method for simultaneous determination of ciprofloxacin and ofloxacin in human urine
- Izabella Kośka
- , Krystian Purgat
- & Paweł Kubalczyk
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| Open AccessApigeninidin-rich Sorghum bicolor (L. Moench) extracts suppress A549 cells proliferation and ameliorate toxicity of aflatoxin B1-mediated liver and kidney derangement in rats
- Solomon E. Owumi
- , Abisola I. Kazeem
- & Adegboyega K. Oyelere
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| Open AccessFive nanometer size highly positive silver nanoparticles are bactericidal targeting cell wall and adherent fimbriae expression
- Lok R. Pokhrel
- , Zachary L. Jacobs
- & Shaw M. Akula
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| Open AccessEffects of intramuscularly injected plant-derived antimicrobials in the mouse model
- Elizabeth J. Johnson
- , Jingyue Ellie Duan
- & Xiuchun Cindy Tian
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Article
| Open AccessIn vitro assessment of skin sensitization, irritability and toxicity of bacteriocins and reuterin for possible topical applications
- Samira Soltani
- , Yvan Boutin
- & Ismail Fliss
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| Open AccessAutomated analysis of activity, sleep, and rhythmic behaviour in various animal species with the Rtivity software
- Rui F. O. Silva
- , Brígida R. Pinho
- & Jorge M. A. Oliveira
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| Open AccessComprehensive assessment of NR ligand polypharmacology by a multiplex reporter NR assay
- Alexander Medvedev
- , Matt Moeser
- & Sergei S. Makarov