Totipotent stem cells articles from across Nature Portfolio
Totipotent stem cells are cells that have the capacity to self-renew by dividing and to develop into the three primary germ cell layers of the early embryo and into extra-embryonic tissues such as the placenta. A fertilised egg is a totipotent stem cell and as such can develop into any specialised cell found in the organism.
Latest Research and Reviews
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Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction
Nature Cell Biology 24, 858-871 -
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Polycomb repressive complex 2 shields naïve human pluripotent cells from trophectoderm differentiation
Nature Cell Biology 24, 845-857 -
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Derivation of totipotent-like stem cells with blastocyst-like structure forming potential
Cell Research 32, 513-529 -
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Rolling back human pluripotent stem cells to an eight-cell embryo-like stage
Nature 605, 315-324
Comparing dormancy in two distantly related tunicates reveals morphological, molecular, and ecological convergences and repeated co-option
Integrated multi-omics reveal polycomb repressive complex 2 restricts human trophoblast induction
Polycomb repressive complex 2 shields naïve human pluripotent cells from trophectoderm differentiation
Derivation of totipotent-like stem cells with blastocyst-like structure forming potential
Rolling back human pluripotent stem cells to an eight-cell embryo-like stage
Cellular redox state as a critical factor in initiating early embryonic-like program in embryonic stem cells