Thymus hormones articles from across Nature Portfolio

Thymus hormones are hormones produced by the thymus. They are generally small proteins, which regulate the development and selection of an immune-competent repertoire of T cells, and stimulate antibody production by B cells. They are important for immune system development and function and also the development of other tissues.

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    T cells are generated in the thymus and exported to peripheral lymphoid organs, a process that is under hormonal control. In this article, the authors discuss the mechanisms of thymus-specific T-cell development and how hormone therapy can counteract the effects of ageing and disease on thymus function.

    • Wilson Savino
    • , Daniella Arêas Mendes-da-Cruz
    •  & Mireille Dardenne
    Nature Reviews Endocrinology 12, 77-89
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