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Thrombotic microangiopathies articles from across Nature Portfolio

Thrombotic microangiopathies are a group of diseases caused by thrombosis in the microvasculature, they most frequently affect the brain and kidneys. Two prominent causes are thrombotic thrombocytopenic purpura and haemolytic uremic syndrome.

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Latest Research and Reviews

Thrombotic microangiopathy in aHUS and beyond: clinical clues from complement genetics

Knowledge of complement genetics has improved understanding of the pathogenesis of primary atypical haemolytic uraemic syndrome (aHUS). This Review summarizes current knowledge of complement genetics in aHUS and discusses how complement studies affect the management of patients with other thrombotic microangiopathies.
- Fadi Fakhouri
- Véronique Frémeaux-Bacchi
Reviews05 May 2021 Nature Reviews Nephrology
Volume: 17, P: 543-553
Shiga toxin signals via ATP and its effect is blocked by purinergic receptor antagonism
- Karl E. Johansson
- Anne-Lie Ståhl
- Diana Karpman
ResearchOpen Access07 Oct 2019 Scientific Reports
Volume: 9, P: 14362
Complement-mediated microangiopathy in IgA nephropathy and IgA vasculitis with nephritis
- Jamie S. Chua
- Malu Zandbergen
- Ingeborg M. Bajema
Research01 Apr 2019 Modern Pathology
Volume: 32, P: 1147-1157
Bevacizumab-associated glomerular microangiopathy
- Fermin Person
- Markus M. Rinschen
- Thorsten Wiech
Research14 Dec 2018 Modern Pathology
Volume: 32, P: 684-700
Radiation-induced premature cellular senescence involved in glomerular diseases in rats
- Sae Aratani
- Masako Tagawa
- Shuichi Tsuruoka
ResearchOpen Access14 Nov 2018 Scientific Reports
Volume: 8, P: 16812
Transplant glomerulopathy
- Edward J Filippone
- Peter A McCue
- John L Farber
Reviews13 Oct 2017 Modern Pathology
Volume: 31, P: 235-252

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News and Comment

The absence of CFHR3 and CFHR1 genes from the T2T-CHM13 assembly can limit the molecular diagnosis of complement-related diseases
- Abderaouf Hamza
- Carine El-Sissy
- Laurent Mesnard
Comments & Opinion10 Apr 2023 European Journal of Human Genetics
Volume: 31, P: 730-732
Pregnancy outcomes in aHUS
- Ellen F. Carney
Research Highlights15 Jan 2018 Nature Reviews Nephrology
Volume: 14, P: 143
Reducing thrombosis in CKD
- Grant Otto
Research Highlights11 Dec 2017 Nature Reviews Nephrology
Volume: 14, P: 72
Inside the USCAP Journals

Comments & Opinion31 Oct 2017 Laboratory Investigation
Volume: 97, P: 1266-1267
Anti-dengue IgG1
- Laurie A Dempsey
Research Highlights15 Feb 2017 Nature Immunology
Volume: 18, P: 254
VEGF–complement interactions
- Susan J. Allison
Research Highlights19 Dec 2016 Nature Reviews Nephrology
Volume: 13, P: 62

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