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Three-dimensional imaging is a technique that combines many scans (from computed tomography, MRI or ultrasonography) computationally. Such images can then be manipulated by the radiographer or physician to aid diagnosis and surgical planning.
This Review summarizes the development of optoacoustic imaging with acoustic resolution and wide-bandwidth ultrasound detection, and the applicability of this mesoscopic imaging modality in the label-free visualization of tissue pathophysiology.