Techniques and instrumentation articles within Nature Methods

Featured

• Technology Feature | 10 March 2023

  Proteomics sets up single-cell and single-molecule solutions

  New instruments are emerging in single-cell and single-molecule proteomics. This will offer labs a choice of technologies.

  • Vivien Marx

• This Month | 06 September 2022

  Hi, new PI

  Your name is on the door to your new lab. Life is getting exciting and turbulent.

  • Vivien Marx

• Technology Feature | 06 June 2022

  Modeling the early embryo

  Widespread adoption of new embryo models hinges on how faithfully they mirror real embryos.

  • Vivien Marx

• Research Highlight | 02 July 2018

  Corrected in vivo imaging

  Aberration correction adds depth to light-sheet microscopy.

  • Zachary J. Lapin

• News & Views | 31 January 2017

  Cool and dynamic: single-molecule fluorescence-based structural biology

  New methods exploit single-molecule measurements to study protein structure and dynamics.

  • Timothy D Craggs

• This Month | 27 May 2011

  The author file: Mats Gustafsson (1960–2011)

  A physicist pushed microscopes beyond theoretical limits to provide a better look inside living cells.

  • Mats G L Gustafsson

• Article | 20 June 2010

  Noncontact microrheology at acoustic frequencies using frequency-modulated atomic force microscopy

  Noncontact, frequency-modulation atomic force microscopy (FM-AFM) can be used to measure the microrheological properties of soft samples at acoustic frequencies. The method will be useful for characterizing the elasticity and viscosity of tissues that detect or produce sound.

  • Núria Gavara
  •  & Richard S Chadwick