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Targeted resequencing is a method that aims to identify causative mutations within discrete genomic loci in populations by isolating and sequencing genomic regions of interest from a sample library. It is one of the fastest growing applications for next-generation sequencing technologies.
capTEs is a long-read targeted RNA-sequencing method that can quantify the expression of reference and non-reference transposable elements at the level of genomic loci.
Two new papers in Nature Biotechnology report methods for targeted sequencing of complex DNA samples, achieved in real time during nanopore sequencing runs.
