Synaptic vesicle endocytosis articles within Nature Communications

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  • Article
    | Open Access

    Synaptic vesicles are efficiently retrieved after transmission but the contribution they make to future signalling remains unclear. Rey et al.find that only a subset of vesicles—typically those retrieved recently in the stimulus train—remain near the active zone and exhibit privileged use.

    • Stephanie A. Rey
    • , Catherine A. Smith
    •  & Kevin Staras
  • Article |

    During development, neurons prune their axons and dendrites to eliminate excessive or inappropriate connections initially formed but the mechanistic details of the pruning process are not completely understood. Here the authors visualize pruning events in dendritic branches in Drosophilaand study the role of calcium transients and endocytosis in this process.

    • Takahiro Kanamori
    • , Jiro Yoshino
    •  & Kazuo Emoto
  • Article
    | Open Access

    Synaptic vesicle endocytosis is required for neurotransmission at nerve terminals. Smillie et al. show that brain-derived neurotrophic factor inhibits a specific type of synaptic vesicle endocytosis, which reverses the depression of neurotransmission observed during high-intensity stimulation.

    • Karen J. Smillie
    • , Jonathan Pawson
    •  & Michael A. Cousin