Sugar phosphates articles from across Nature Portfolio

Glycosyl phosphosaccharides represent a large and important family of complex glycans, but are difficult to synthesize efficiently. Here, the authors disclose a stereoselective methodology to make α-glycosyl phosphosaccharides, via gold(I)-catalyzed glycosylation of phosphoric acid acceptors.

Myo-Inositol phosphates (InsPs) and pyrophosphates (PP-InsPs) are important second messengers but their analysis remains challenging. Here, the authors develop a capillary electrophoresis-mass spectrometry method for the identification and quantitation of InsP and PP-InsP isomers in cells and tissues.

Treatment with signalling precursors of trehalose-6-phosphate allows light-triggered release of trehalose-6-phosphate in Arabidopsis thaliana and increases the yield and drought resistance of spring wheat (Triticum aestivum).