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| Open AccessConformational Change of a Tryptophan Residue in BtuF Facilitates Binding and Transport of Cobinamide by the Vitamin B12 Transporter BtuCD-F
- S. A. Mireku
- , M. Ruetz
- & K. P. Locher
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| Open AccessComputational design of an epitope-specific Keap1 binding antibody using hotspot residues grafting and CDR loop swapping
- Xiaofeng Liu
- , Richard D. Taylor
- & Terry Baker
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| Open AccessMycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors
- Daniel H. Haft
- , Phillip G. Pierce
- & Thomas E. Edwards
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| Open AccessThe Matrix protein M1 from influenza C virus induces tubular membrane invaginations in an in vitro cell membrane model
- David Saletti
- , Jens Radzimanowski
- & Marta Bally
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| Open AccessLigand binding pocket of a novel Allatostatin receptor type C of stick insect, Carausius morosus
- Burcin Duan Sahbaz
- , Osman Ugur Sezerman
- & Necla Birgül Iyison
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| Open AccessDesign of an expression system to enhance MBP-mediated crystallization
- Tengchuan Jin
- , Watchalee Chuenchor
- & Tsan Sam Xiao
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| Open AccessA conserved TLR5 binding and activation hot spot on flagellin
- Wan Seok Song
- , Ye Ji Jeon
- & Sung-il Yoon
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| Open AccessTime-resolved neutron scattering provides new insight into protein substrate processing by a AAA+ unfoldase
- Ziad Ibrahim
- , Anne Martel
- & Frank Gabel
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| Open AccessCrystal structure of Sec10, a subunit of the exocyst complex
- Jianxing Chen
- , Atsushi Yamagata
- & Shuya Fukai
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| Open AccessMolecular mechanism of the allosteric regulation of the αγ heterodimer of human NAD-dependent isocitrate dehydrogenase
- Tengfei Ma
- , Yingjie Peng
- & Jianping Ding
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| Open AccessMethylation specific targeting of a chromatin remodeling complex from sponges to humans
- Jason M. Cramer
- , Deborah Pohlmann
- & David C. Williams Jr.
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| Open AccessUltrastructure of sensilla of antennae and ovipositor of Sitotroga cerealella (Lepidoptera: Gelechiidae), and location of female sex pheromone gland
- Min Ma
- , Meng-Meng Chang
- & Feng-Lian Yang
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| Open AccessHigh resolution structural evidence suggests the Sarcoplasmic Reticulum forms microdomains with Acidic Stores (lysosomes) in the heart
- Daniel Aston
- , Rebecca A. Capel
- & Derek A. Terrar
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| Open AccessStructural basis of the interaction between the putative adhesion-involved and iron-regulated FrpD and FrpC proteins of Neisseria meningitidis
- Ekaterina Sviridova
- , Pavlina Rezacova
- & Ladislav Bumba
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| Open AccessHigh response speed microfluidic ice valves with enhanced thermal conductivity and a movable refrigeration source
- Chaorun Si
- , Songtao Hu
- & Weichao Wu
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| Open AccessX-ray Structure and Enzymatic Activity Profile of a Core Papain-like Protease of MERS Coronavirus with utility for structure-based drug design
- Jozlyn R. Clasman
- , Yahira M. Báez-Santos
- & Andrew D. Mesecar
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| Open AccessCrystal Structure of StnA for the Biosynthesis of Antitumor Drug Streptonigrin Reveals a Unique Substrate Binding Mode
- Tianle Qian
- , Jing Wo
- & Hai-Feng Chen
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| Open AccessNucleoplasmin-like domain of FKBP39 from Drosophila melanogaster forms a tetramer with partly disordered tentacle-like C-terminal segments
- Małgorzata Kozłowska
- , Aneta Tarczewska
- & Andrzej Ożyhar
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| Open AccessNew insights into the GINS complex explain the controversy between existing structural models
- Marta Carroni
- , Matteo De March
- & Silvia Onesti
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| Open AccessThe mechanism of catalysis by type-II NADH:quinone oxidoreductases
- James N. Blaza
- , Hannah R. Bridges
- & Judy Hirst
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Article
| Open AccessNMR reveals a dynamic allosteric pathway in thrombin
- Lindsey D. Handley
- , Brian Fuglestad
- & Elizabeth A. Komives
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Article
| Open AccessStructure of the acetophenone carboxylase core complex: prototype of a new class of ATP-dependent carboxylases/hydrolases
- Sina Weidenweber
- , Karola Schühle
- & Johann Heider
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| Open AccessIdentification of a Drug Targeting an Intrinsically Disordered Protein Involved in Pancreatic Adenocarcinoma
- José L. Neira
- , Jennifer Bintz
- & Olga Abián
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| Open AccessAtomic scale chemical tomography of human bone
- Brian Langelier
- , Xiaoyue Wang
- & Kathryn Grandfield
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| Open AccessIntercalative DNA binding of the marine anticancer drug variolin B
- Albert Canals
- , Raquel Arribas-Bosacoma
- & Miquel Coll
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| Open AccessU24 from Roseolovirus interacts strongly with Nedd4 WW Domains
- Yurou Sang
- , Rui Zhang
- & Suzana K. Straus
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| Open AccessMechanisms of Yersinia YopO kinase substrate specificity
- Wei Lin Lee
- , Pavithra Singaravelu
- & Robert C. Robinson
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| Open AccessStructural characterisation of the fatty acid biosynthesis enzyme FabF from the pathogen Listeria monocytogenes
- Tatiana P. Soares da Costa
- , Jeffrey D. Nanson
- & Jade K. Forwood
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| Open AccessDisruption of cell adhesion by an antibody targeting the cell-adhesive intermediate (X-dimer) of human P-cadherin
- Shota Kudo
- , Jose M. M. Caaveiro
- & Kouhei Tsumoto
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| Open AccessBiochemical and structural characterization of a novel halotolerant cellulase from soil metagenome
- Roma Garg
- , Ritika Srivastava
- & Girish Sahni
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Article
| Open AccessThe Crystal Structure of Monovalent Streptavidin
- Min Zhang
- , Sangita Biswas
- & Hongjun Yu
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| Open AccessHigh resolution crystal structure of the catalytic domain of MCR-1
- Guixing Ma
- , Yifan Zhu
- & Hongmin Zhang
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| Open AccessStructure-based rationale for differential recognition of lacto- and neolacto- series glycosphingolipids by the N-terminal domain of human galectin-8
- Mohammad H. Bohari
- , Xing Yu
- & Helen Blanchard
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| Open AccessStructural basis of the substrate preference towards CMP for a thymidylate synthase MilA involved in mildiomycin biosynthesis
- Gong Zhao
- , Cheng Chen
- & Xinyi He
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| Open AccessStructure of Crenezumab Complex with Aβ Shows Loss of β-Hairpin
- Mark Ultsch
- , Bing Li
- & Weiru Wang
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| Open AccessThree-dimensional ultrastructural analysis of cells in the periodontal ligament using focused ion beam/scanning electron microscope tomography
- Shingo Hirashima
- , Keisuke Ohta
- & Kei-ichiro Nakamura
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| Open AccessProtein knotting through concatenation significantly reduces folding stability
- Shang-Te Danny Hsu
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| Open AccessInvestigating the human Calcineurin Interaction Network using the πɸLxVP SLiM
- Sarah R. Sheftic
- , Rebecca Page
- & Wolfgang Peti
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| Open AccessStructural implications of Ca2+-dependent actin-bundling function of human EFhd2/Swiprosin-1
- Kyoung Ryoung Park
- , Min-Sung Kwon
- & Soo Hyun Eom
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| Open AccessResilin microjoints: a smart design strategy to avoid failure in dragonfly wings
- H. Rajabi
- , A. Shafiei
- & S. N. Gorb
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| Open AccessA novel pleuromutilin antibacterial compound, its binding mode and selectivity mechanism
- Zohar Eyal
- , Donna Matzov
- & Ada Yonath
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| Open AccessStructural Basis for Human PECAM-1-Mediated Trans-homophilic Cell Adhesion
- Menglong Hu
- , Hongmin Zhang
- & Quan Hao
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| Open AccessCrystal Structure of Escherichia coli originated MCR-1, a phosphoethanolamine transferase for Colistin Resistance
- Menglong Hu
- , Jiubiao Guo
- & Quan Hao
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| Open AccessGenetically targeted 3D visualisation of Drosophila neurons under Electron Microscopy and X-Ray Microscopy using miniSOG
- Julian Ng
- , Alyssa Browning
- & Gregory S. X. E. Jefferis
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| Open AccessFunctional and structural characterization of a novel putative cysteine protease cell wall-modifying multi-domain enzyme selected from a microbial metagenome
- Muhammad Faheem
- , Diogo Martins-de-Sa
- & João Alexandre R. G. Barbosa
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| Open AccessStructural Analysis of Glycine Sarcosine N-methyltransferase from Methanohalophilus portucalensis Reveals Mechanistic Insights into the Regulation of Methyltransferase Activity
- Yi-Ru Lee
- , Te-Sheng Lin
- & Nei-Li Chan
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| Open AccessThe mechanism of a formaldehyde-sensing transcriptional regulator
- Katie J. Denby
- , Jeffrey Iwig
- & Jeffrey Green
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| Open AccessA central cavity within the holo-translocon suggests a mechanism for membrane protein insertion
- Mathieu Botte
- , Nathan R. Zaccai
- & Christiane Schaffitzel
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| Open AccessDiverse specificity of cellulosome attachment to the bacterial cell surface
- Joana L. A. Brás
- , Benedita A. Pinheiro
- & Carlos M. G. A. Fontes