Stem cells in the nervous system

Stem cells in the nervous system are self-renewing cells that have the capacity to produce all, or a restricted set of, the neural cell types (neurons and glia) in the nervous system. Stem cells can be found in the developing and adult nervous system.

Latest Research and Reviews

Research
10 August 2022 | Open Access

A non-invasive system to monitor in vivo neural graft activity after spinal cord injury

Visualisation of the activity of neural grafts using engineered luciferase provides insights into the integration between the graft and host.
- Kentaro Ago
- , Narihito Nagoshi
- & Hideyuki Okano
Communications Biology 5, 803
Research
15 July 2022 | Open Access

Transcription-associated DNA DSBs activate p53 during hiPSC-based neurogenesis
- Nadine Michel
- , Heather M. Raimer Young
- & Michael J. McConnell
Scientific Reports 12, 12156
Research
01 June 2022 | Open Access

Human cerebral spheroids undergo 4-aminopyridine-induced, activity associated changes in cellular composition and microrna expression
- Thomas Parmentier
- , Fiona M. K. James
- & Jonathan LaMarre
Scientific Reports 12, 9143
Research
23 May 2022 | Open Access

Signal requirement for cortical potential of transplantable human neuroepithelial stem cells

The regulatory pathways that control the human neural progenitor cell pool are not well understood. Here, Varga et al. identify signals that control the division of human pluripotent stem cell derived neural stem cells and their ability to make cortical neurons and glia.
- Balazs V. Varga
- , Maryam Faiz
- & Andras Nagy
Nature Communications 13, 2844
Research
13 April 2022 | Open Access

Oscillatory calcium release and sustained store-operated oscillatory calcium signaling prevents differentiation of human oligodendrocyte progenitor cells
- Richard A. Seidman
- , Heba Khattab
- & Fraser J. Sim
Scientific Reports 12, 6160
Research
28 March 2022 | Open Access

Rational design and synthesis of a novel BODIPY-based probe for selective imaging of tau tangles in human iPSC-derived cortical neurons
- Alessandro Soloperto
- , Deborah Quaglio
- & Alberto Boffi
Scientific Reports 12, 5257

All Research & Reviews

News and Comment

Research Highlights | 25 May 2022

A hypothalamic boost for neurogenesis

Neuronal activity in a key region of the mouse hypothalamus modulates adult hippocampal neurogenesis, promoting the formation of adult-born neurons that support cognition and affective function.
- Katherine Whalley
Nature Reviews Neuroscience 23, 391
Research Highlights | 14 December 2021

Interspecies differences
- Sian Lewis
Nature Reviews Neuroscience 23, 69
Research Highlights | 02 September 2021

Organoid modelling of network function

Cortical–subcortical fusion organoids replicate complex features of human brain activity and are used to explore altered network function in Rett syndrome.
- Katherine Whalley
Nature Reviews Neuroscience 22, 654-655
Research Highlights | 07 April 2021

Shape-shifting organoids
- Sian Lewis
Nature Reviews Neuroscience 22, 261
Research Highlights | 16 July 2020

‘Enhancing’ brain maturation

Postnatal brain development is highly influenced by sensory experience, in part via de novo activation of enhancer sequences by inducible transcription factors.
- Sian Lewis
Nature Reviews Neuroscience 21, 450-451
Research Highlights | 02 March 2020

New nose neurons
- Sian Lewis
Nature Reviews Neuroscience 21, 182

All News & Comment

Stem cells in the nervous system

Latest Research and Reviews

A non-invasive system to monitor in vivo neural graft activity after spinal cord injury

Transcription-associated DNA DSBs activate p53 during hiPSC-based neurogenesis

Human cerebral spheroids undergo 4-aminopyridine-induced, activity associated changes in cellular composition and microrna expression

Signal requirement for cortical potential of transplantable human neuroepithelial stem cells

Oscillatory calcium release and sustained store-operated oscillatory calcium signaling prevents differentiation of human oligodendrocyte progenitor cells

Rational design and synthesis of a novel BODIPY-based probe for selective imaging of tau tangles in human iPSC-derived cortical neurons

News and Comment

A hypothalamic boost for neurogenesis

Interspecies differences

Organoid modelling of network function

Shape-shifting organoids

‘Enhancing’ brain maturation

New nose neurons

Quick links

Discover content

Publishing policies

Author & Researcher services

Libraries & institutions

Advertising & partnerships

Career development

Regional websites

Legal & Privacy

Stem cells in the nervous system

Related Subjects

Latest Research and Reviews

News and Comment

Search

Quick links