Solid-state NMR

Solid-state nuclear magnetic resonance (ssNMR) spectroscopy is a variant of the NMR spectroscopy technique used for molecular structure determination, where the experimental sample is contained in media with little or no mobility (such as, a crystalline or powder state, membrane-bound system or aligned solution).

Latest Research and Reviews

News and Comment

  • Research Highlights |

    A newly developed method allows structure elucidation of proteins inside intact mammalian cells, using solid-state NMR spectroscopy.

    • Arunima Singh
    Nature Methods 16, 676
  • News and Views |

    Sporopollenin, which encapsulates gametes in spore and pollen grains, is probably the most chemically inert biopolymer. This inertness is essential for gamete protection, but also hinders the elucidation of sporopollenin molecular structure. Now, the macromolecular network forming sporopollenin is described in unprecedented detail.

    • Paula Guzmán-Delgado
    •  & Maciej A. Zwieniecki
  • News and Views |

    Generating pure spin currents is a necessary part of many spintronic devices. Now there is a new mechanism for doing this, utilizing nuclear spin waves.

    • Claudia K. A. Mewes
    Nature Physics 15, 8-9
  • Editorial |

    In a common yet effective analogy, a cell can be compared to a fortified city, in which lipid membranes form the defensive walls, and membrane proteins function as gates and checkpoints that control the transit of molecules and information across these walls. We evoke this concept on the cover of this special Focus on Membrane Proteins.

  • News and Views |

    All current evidence indicates a central role for α-synuclein (α-SYN) amyloid fibrils in Parkinson's disease and other synucleinopathies, but the precise relationship between amyloid aggregates and the resulting phenotype remains poorly understood, partly because of the lack of reliable three-dimensional structures. In this issue, the structure of a toxic α-SYN fibril is now presented at unprecedented resolution.

    • Wouter Peelaerts
    •  & Veerle Baekelandt