Small-cell lung cancer
Small-cell lung cancer is a highly malignant form of lung cancer, also known as oat-cell carcinoma, that accounts for approximately 15% of lung cancer cases. Composed of small, ovoid cells with very little cytoplasm, small-cell lung cancer usually originates in the bronchi and is caused by smoking.
Latest Research and Reviews
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Research
| Open Access
NEMO- and RelA-dependent NF-κB signaling promotes small cell lung cancer
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Research
| Open Access
Radiotherapy in combination with CD47 blockade elicits a macrophage-mediated abscopal effect
Nature Cancer 3, 1351-1366 -
Identifying CDC7 as a synergistic target of chemotherapy in resistant small-cell lung cancer via CRISPR/Cas9 screening
NEMO- and RelA-dependent NF-κB signaling promotes small cell lung cancer
Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibit small-cell lung cancer growth without causing on-target toxicities in mice
Molecular features and evolutionary trajectory of ASCL1+ and NEUROD1+ SCLC cells
Radiotherapy in combination with CD47 blockade elicits a macrophage-mediated abscopal effect
Exosomal miR-328 originated from pulmonary adenocarcinoma cells enhances osteoclastogenesis via downregulating Nrp-2 expression
Selective regulation of tuft cell-like small cell lung cancer by novel transcriptional co-activators C11orf53 and COLCA2
Back to the beginning to understand metastasis