SARS virus

SARS virus is an infectious agent belonging to the virus family Coronaviridae, which causes severe respiratory illnesses in humans and animals. SARS (severe acute respiratory syndrome) coronavirus (CoV) is a novel member of this family that causes acute respiratory distress syndrome (ARDS), which is associated with high mortality rates.

Latest Research and Reviews

  • Research |

    Bat and human intestinal organoids can support replication of SARS-CoV-2, enabling further characterization of the virus lifecycle and investigation of potential mechanisms of enteric infection in COVID-19.

    • Jie Zhou
    • , Cun Li
    • , Xiaojuan Liu
    • , Man Chun Chiu
    • , Xiaoyu Zhao
    • , Dong Wang
    • , Yuxuan Wei
    • , Andrew Lee
    • , Anna Jinxia Zhang
    • , Hin Chu
    • , Jian-Piao Cai
    • , Cyril Chik-Yan Yip
    • , Ivy Hau-Yee Chan
    • , Kenneth Kak-Yuen Wong
    • , Owen Tak-Yin Tsang
    • , Kwok-Hung Chan
    • , Jasper Fuk-Woo Chan
    • , Kelvin Kai-Wang To
    • , Honglin Chen
    •  & Kwok Yung Yuen
  • Research |

    • Vincent J. Munster
    • , Friederike Feldmann
    • , Brandi N. Williamson
    • , Neeltje van Doremalen
    • , Lizzette Pérez-Pérez
    • , Jonathan Schulz
    • , Kimberly Meade-White
    • , Atsushi Okumura
    • , Julie Callison
    • , Beniah Brumbaugh
    • , Victoria A. Avanzato
    • , Rebecca Rosenke
    • , Patrick W. Hanley
    • , Greg Saturday
    • , Dana Scott
    • , Elizabeth R. Fischer
    •  & Emmie de Wit
    Nature, 1-7
  • Research |

    Infection with SARS-CoV-2 causes interstitial pneumonia and viral replication in the lungs of transgenic mice that express a human version of ACE2, confirming the pathogenicity of the virus in this model.

    • Linlin Bao
    • , Wei Deng
    • , Baoying Huang
    • , Hong Gao
    • , Jiangning Liu
    • , Lili Ren
    • , Qiang Wei
    • , Pin Yu
    • , Yanfeng Xu
    • , Feifei Qi
    • , Yajin Qu
    • , Fengdi Li
    • , Qi Lv
    • , Wenling Wang
    • , Jing Xue
    • , Shuran Gong
    • , Mingya Liu
    • , Guanpeng Wang
    • , Shunyi Wang
    • , Zhiqi Song
    • , Linna Zhao
    • , Peipei Liu
    • , Li Zhao
    • , Fei Ye
    • , Huijuan Wang
    • , Weimin Zhou
    • , Na Zhu
    • , Wei Zhen
    • , Haisheng Yu
    • , Xiaojuan Zhang
    • , Li Guo
    • , Lan Chen
    • , Conghui Wang
    • , Ying Wang
    • , Xinming Wang
    • , Yan Xiao
    • , Qiangming Sun
    • , Hongqi Liu
    • , Fanli Zhu
    • , Chunxia Ma
    • , Lingmei Yan
    • , Mengli Yang
    • , Jun Han
    • , Wenbo Xu
    • , Wenjie Tan
    • , Xiaozhong Peng
    • , Qi Jin
    • , Guizhen Wu
    •  & Chuan Qin
    Nature, 1-4
  • Research |

    A newly identified coronavirus found in Malayan pangolins shares considerable sequence identity with SARS-CoV-2, which suggests that the latter may have originated from a recombination event involving SARS-related coronaviruses from bats and pangolins.

    • Kangpeng Xiao
    • , Junqiong Zhai
    • , Yaoyu Feng
    • , Niu Zhou
    • , Xu Zhang
    • , Jie-Jian Zou
    • , Na Li
    • , Yaqiong Guo
    • , Xiaobing Li
    • , Xuejuan Shen
    • , Zhipeng Zhang
    • , Fanfan Shu
    • , Wanyi Huang
    • , Yu Li
    • , Ziding Zhang
    • , Rui-Ai Chen
    • , Ya-Jiang Wu
    • , Shi-Ming Peng
    • , Mian Huang
    • , Wei-Jun Xie
    • , Qin-Hui Cai
    • , Fang-Hui Hou
    • , Wu Chen
    • , Lihua Xiao
    •  & Yongyi Shen
    Nature, 1-4
  • Research |

    A yeast-based synthetic genomics platform is used to reconstruct and characterize large RNA viruses from synthetic DNA fragments; this technique will facilitate the rapid analysis of RNA viruses, such as SARS-CoV-2, during an outbreak.

    • Tran Thi Nhu Thao
    • , Fabien Labroussaa
    • , Nadine Ebert
    • , Philip V’kovski
    • , Hanspeter Stalder
    • , Jasmine Portmann
    • , Jenna Kelly
    • , Silvio Steiner
    • , Melle Holwerda
    • , Annika Kratzel
    • , Mitra Gultom
    • , Kimberly Schmied
    • , Laura Laloli
    • , Linda Hüsser
    • , Manon Wider
    • , Stephanie Pfaender
    • , Dagny Hirt
    • , Valentina Cippà
    • , Silvia Crespo-Pomar
    • , Simon Schröder
    • , Doreen Muth
    • , Daniela Niemeyer
    • , Victor M. Corman
    • , Marcel A. Müller
    • , Christian Drosten
    • , Ronald Dijkman
    • , Joerg Jores
    •  & Volker Thiel
    Nature 582, 561-565

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