Rotavirus

A recent study found that constituents of the gut virome are negatively associated with seroconversion following rotavirus vaccination, possibly explaining the diminished effectiveness of rotavirus vaccines in low- and middle-income countries.

This study provides structural insights into how the rotavirus spike protein VP4 undergoes a conformational change to initiate host membrane disruption during infection.

A recent study provides new evidence that rotavirus-infected cells produce pancrine signals that uninfected cells respond to, leading to intercellular calcium waves and ultimately to diarrhoea.

This study finds that gut segmented filamentous bacteria prevent and cure rotavirus infection in immunodeficient mice.

This study shows that rotaviruses and noroviruses are transmitted in stool as clusters of viruses within vesicles, and that this mode of transmission provides a replication advantage.