RNA vaccines articles from across Nature Portfolio

RNA vaccines are composed of the nucleic acid RNA, which encode antigen genes of an infectious agent. When administered to host cells, the RNA is translated into protein antigens that elicit protective immunity against the infectious agent.

Latest Research and Reviews

Research
07 June 2023 | Open Access

A mosquito AgTRIO mRNA vaccine contributes to immunity against malaria
- Yu-Min Chuang
- , Mohamad-Gabriel Alameh
- & Erol Fikrig
npj Vaccines 8, 88
Research
06 June 2023 | Open Access

GRT-R910: a self-amplifying mRNA SARS-CoV-2 vaccine boosts immunity for ≥6 months in previously-vaccinated older adults

Palmer et al. present interim findings from their clinical trial; they describe the reactogenicity and immunogenicity results of a self-amplifying mRNA SARS-CoV-2 booster vaccine within an older population (≥60 years of age).
- Christine D. Palmer
- , Ciaran D. Scallan
- & Andrew Ustianowski
Nature Communications 14, 3274
Research
05 June 2023 | Open Access

Analyzing immune responses to varied mRNA and protein vaccine sequences
- Hyeong-Jun Park
- , Yoo-Jin Bang
- & Jae-Hwan Nam
npj Vaccines 8, 84
Research
03 June 2023 | Open Access

Oligonucleotide mapping via mass spectrometry to enable comprehensive primary structure characterization of an mRNA vaccine against SARS-CoV-2
- Brian C. Gau
- , Andrew W. Dawdy
- & Jason C. Rouse
Scientific Reports 13, 9038
Research
03 June 2023 | Open Access

Impact of timing and combination of different BNT162b2 and ChAdOx1-S COVID-19 basic and booster vaccinations on humoral immunogenicity and reactogenicity in adults
- Simon Dedroogh
- , Sven Schmiedl
- & Michael Dedroogh
Scientific Reports 13, 9036
Research
01 June 2023 | Open Access

Epigenomic landscape exhibits interferon signaling suppression in the patient of myocarditis after BNT162b2 vaccination
- Hyeonhui Kim
- , Hyo-Suk Ahn
- & Sungsoon Fang
Scientific Reports 13, 8926

All Research & Reviews

News and Comment

Research Highlights | 24 April 2023

Primary vaccination imprint
- Ioana Visan
Nature Immunology 24, 732
Research Highlights | 23 March 2023

Vaccine-induced memory
- Ioana Visan
Nature Immunology 24, 560
Research Highlights | 23 January 2023

Leveraging the power of crowds
- Fernando Chirigati
Nature Computational Science 3, 2
News & Views | 20 December 2022

Towards a universal flu vaccine
- Cristina Lo Giudice
Nature Materials 22, 407
Comments & Opinion | 20 December 2022

Impact of anti-PEG antibodies induced by SARS-CoV-2 mRNA vaccines

The successful mRNA vaccines against COVID-19 contain polyethylene glycol (PEG) to stabilize the lipid nanoparticles. Recent data show that PEG-specific antibodies can be induced or boosted by mRNA vaccination. Further research is needed to study the potential links between PEG-specific antibodies, vaccine reactogenicity and enhanced clearance of other PEG-containing medicines.
- Yi Ju
- , Juan Manuel Carreño
- & Stephen J. Kent
Nature Reviews Immunology 23, 135-136
Research Highlights | 14 December 2022

Broad protection from a single flu vaccine

Arevalo et al. have developed a nucleoside-modified mRNA-lipid nanoparticle vaccine encoding separate haemagglutinin antigens from all known influenza virus subtypes.
- Michael Attwaters
Nature Reviews Microbiology 21, 67

All News & Comment

RNA vaccines articles from across Nature Portfolio

Latest Research and Reviews

A mosquito AgTRIO mRNA vaccine contributes to immunity against malaria

GRT-R910: a self-amplifying mRNA SARS-CoV-2 vaccine boosts immunity for ≥6 months in previously-vaccinated older adults

Analyzing immune responses to varied mRNA and protein vaccine sequences

Oligonucleotide mapping via mass spectrometry to enable comprehensive primary structure characterization of an mRNA vaccine against SARS-CoV-2

Impact of timing and combination of different BNT162b2 and ChAdOx1-S COVID-19 basic and booster vaccinations on humoral immunogenicity and reactogenicity in adults

Epigenomic landscape exhibits interferon signaling suppression in the patient of myocarditis after BNT162b2 vaccination

News and Comment

Primary vaccination imprint

Vaccine-induced memory

Leveraging the power of crowds

Towards a universal flu vaccine

Impact of anti-PEG antibodies induced by SARS-CoV-2 mRNA vaccines

Broad protection from a single flu vaccine

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