Proteins

Proteins are biopolymers of amino acids (polypeptides), joined by peptide bonds, that are generated by ribosomes. The amino acid sequence, encoded by its gene, determines a protein’s structure and function. Newly synthesized proteins can be modified by post-translational modification, altering its protein folding, stability and activity. Proteins often associate into protein–protein interaction networks for function.

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News and Comment

  • News and Views |

    The observation of a room-temperature stable liquid phase of electrons and holes in a quasi-two-dimensional photocell paves the way towards optoelectronic devices that harness collective phenomena.

    • Stéphane Berciaud
    Nature Photonics 13, 225-226
  • Research Highlights |

    Formylglycine residues are important functional handles on native and synthetic proteins. The formation of these residues is mediated by a copper enzyme operating via a superoxo intermediate.

    • David Schilter
  • Research Highlights |

    Nair et al. contrast events at specific super-enhancers after acute and chronic ligand-induced activation and show that biomolecular condensates at these enhancers undergo physical changes over time that affect chromatin conformation and gene expression.

    • Linda Koch