Proteases articles from across Nature Portfolio

Proteases are enzymes that catalyse hydrolysis of the peptide and isopeptide bonds that join amino acids within proteins (known as proteolysis). Proteases can also remove protein post-translational modifications. Exopeptidases remove the terminal amino acids from the protein chain and endopeptidases attack an internal peptide bond, as in trypsin, chymotrypsin, pepsin, elastase and papain.


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