Process chemistry

Process chemistry involves the development and optimization of production processes for chemical compounds, and the scaling up of laboratory reactions, particularly in the pharmaceutical sector.

Latest Research and Reviews

News and Comment

  • News & Views |

    Sustainable recycling is necessary for wood to maintain its capacity to store CO2 and to smooth the transition towards a circular economy. Now, an innovative approach offers a promising perspective on second- and third-life applications for ‘waste’ wood.

    • Guido Panzarasa
    •  & Ingo Burgert
  • Comments & Opinion
    | Open Access

    Carbon mineralization is a versatile and thermodynamically downhill process that can be harnessed for capturing, storing, and utilizing CO2 to synthesize products with enhanced properties. Here the author discusses the advances in and challenges of carbon mineralization, and concludes that tuning the chemical interactions involved will allow us to unlock its potential for advancing low carbon energy and resource conversion pathways.

    • Greeshma Gadikota
  • Comments & Opinion
    | Open Access

    Can organic chemistry mimic nature in efficiency and sustainability? Not yet, but recent developments in photoredox catalysis animated the synthetic chemistry field, providing greener opportunities for industry and academia.

    • Giacomo E. M. Crisenza
    •  & Paolo Melchiorre
  • News & Views |

    Imine reductases are promising catalysts, facilitating a direct stereoselective route to secondary amines. Now, protein engineering has created stable and efficient variants that allow their application in kilogram-scale synthesis.

    • Matthias Höhne
    Nature Catalysis 2, 841-842
  • News & Views |

    Scientific progress often relies on applying published methodological advances to different problems. With the aim of improving both the uptake and reproducibility of chemical transformations, a new assessment tool has now been developed that provides a clear and easy-to-interpret overview of common factors that affect a synthetic method.

    • James J. Douglas
    Nature Chemistry 11, 683-684
  • Research Highlights |

    A rapid synthesis of the antibacterial drug linezolid using flow chemistry has been reported that does not require isolation or purification of any intermediates and is completed in seven synthetic steps

    • Stephen G. Davey