Prenylation articles within Nature

Featured

  • Letter |

    The X-ray structure of the integral membrane protein isoprenylcysteine carboxyl methyltransferase suggests mechanisms by which it recognizes both water-soluble and membrane-bound reactants to catalyze the methylation of RAS and other CAAX proteins at the membrane-cytosol interface.

    • Melinda M. Diver
    • , Leanne Pedi
    •  & Stephen B. Long
  • Letter |

    These authors identify the human enzyme responsible for menaquinone-4 biosynthesis, a naturally occurring form of vitamin K. They find that UbiA prenyltransferase containing 1, a human homologue of a prenyltransferase gene from Escherichia coli, encodes an enzyme that can convert vitamin K derivatives into menaquinone-4.

    • Kimie Nakagawa
    • , Yoshihisa Hirota
    •  & Toshio Okano